Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05895500 · ClinicalTrials.gov registry record

Evaluate the Safety and Efficacy of Calcitonin Gene-Related Peptide (CGRP) Antagonists in Patients With Dry Eye Disease and Asthenopia

A clinical trial of Dry Eye and Asthenopia, sponsored by Nvision Laser Eye Centers.

Completed
Registry status
103
Enrollment target
1
Study location

NCT05895500: Completed study of Dry Eye and Asthenopia, sponsored by Nvision Laser Eye Centers.

NCT05895500 is a study of Dry Eye and Asthenopia that has completed, run by Nvision Laser Eye Centers. The registered enrollment target is 103 participants, above the 93-participant average among 41 other Dry Eye trials with a reported enrollment target (11% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05895500, a study of Dry Eye and Asthenopia, has completed, sponsored by Nvision Laser Eye Centers.

COMPLETED
Registry status
103 participants
Enrollment target
1
Study location

Study Summary

Safety and Efficacy of Medications for Migraine in Patients with Dry Eye Disease or Asthenopia

Primary Outcome

Improvement in Symptoms: Number of days that a participant feels improvement in subjective symptoms of eye discomfort due to DED or asthenopia after oral administration of tablets over the 28-day Treatment Period (Days 1 to 28) compared to the 28-day Pretreatment Period (Day -28 to Day -1).

Conditions Studied

Interventions

  • DRUG Injection for SC administration (120mg/syringe)
  • DRUG Tablet (50mg/tablet), oral

Study Locations (1)

California

  • NVision-EWEI-Torrance - Torrance

Trial Details

FieldValue
Enrollment Target 103 participants
Start Date 2023-05-10
Est. Completion 2023-11-09
Nvision Laser Eye Centers

2 total trials

What the finished NCT05895500 record still lists

NCT05895500 is an observational study that tracks outcomes without assigning an intervention. The registered 103 participants enrollment target is mid-sized for trials with a published cap, above the 93-participant average among 41 other Dry Eye trials with a reported enrollment target (11% higher).

The record links to 2 conditions, with Dry Eye appearing as the primary indexed condition, and to 2 interventions - of which Injection for SC administration (120mg/syringe) is the first listed.

NCT05895500 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT05895500 about?

NCT05895500 is a clinical study titled "Evaluate the Safety and Efficacy of Calcitonin Gene-Related Peptide (CGRP) Antagonists in Patients With Dry Eye Disease and Asthenopia". Safety and Efficacy of Medications for Migraine in Patients with Dry Eye Disease or Asthenopia

What is the current status of trial NCT05895500?

This trial is currently completed. The enrollment target is 103 participants. The study started on 2023-05-10. Estimated completion is 2023-11-09.

What conditions does trial NCT05895500 study?

This clinical trial studies the following conditions: Dry Eye, Asthenopia.

What interventions are being tested in trial NCT05895500?

The interventions under investigation include: Injection for SC administration (120mg/syringe) (DRUG), Tablet (50mg/tablet), oral (DRUG).

Who is sponsoring clinical trial NCT05895500?

This trial is sponsored by Nvision Laser Eye Centers, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05895500 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Dry Eye

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05895500's enrollment target sits among peer trials

103 12th of 41 higher than 30 of 41 other Dry Eye trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Dry Eye trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT04690348 · 103 participants · Phase 2

    Intracavitary Carrier-embedded Cs131 Brachytherapy for Recurrent Brain Metastases: a Randomized Phase II Study

  • NCT05282277 · 103 participants · Phase 4

    Examining the Effects of Estradiol on Neural and Molecular Response to Reward

  • NCT05566769 · 103 participants · NA

    Performance and Safety of a Digital Tool for Unsupervised Self-assessment of NMOSD

  • NCT05834478 · 103 participants · Phase 3

    Non-invasive Vagal Nerve Stimulation in Opioid Use Disorders UH3

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT05895500, the US trial registry maintained by the National Library of Medicine. NCT05895500 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.