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NCT05881278 · ClinicalTrials.gov registry record · NA
XVIVO Heart Perfusion System (XHPS) With Supplemented XVIVO Heart Solution (SXHS)
A NA study of Heart Failure and Transplant; Failure, Heart, sponsored by XVIVO Perfusion.
- Active
- Registry status
- NA
- Development phase
- 141
- Enrollment target
- 20
- Study locations
NCT05881278: Active NA study of Heart Failure and Transplant; Failure, Heart, sponsored by XVIVO Perfusion.
NCT05881278 is a NA study of Heart Failure and Transplant; Failure, Heart that is active but no longer recruiting, run by XVIVO Perfusion. The registered enrollment target is 141 participants, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (93% lower). The trial reports 20 study locations across 13 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05881278, a NA study of Heart Failure and Transplant; Failure, Heart, is active but no longer recruiting, sponsored by XVIVO Perfusion.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 141 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to evaluate if Non-Ischemic Heart Preservation (NIHP) of extended criteria donor hearts using the XVIVO Heart Preservation System (XHPS) is a safe and effective way to preserve and transport hearts for transplantation.
Primary Outcome
The percentage of patient survival at 365 days from the date of transplant. The long-term safety success is defined as survival.
Conditions Studied
Interventions
- DEVICE Non-Ischemic Heart Preservation (NIHP) using the XVIVO Heart Preservation System (XHPS)
Study Locations (20)
California
- University of California San Diego - La Jolla
- Cedars-Sinai - Los Angeles
- David Geffen School of Medicine at UCLA - Los Angeles
- Stanford Medicine - Palo Alto
New York
- NYU Langone Health - New York
- Columbia University Irving Medical Center/New York Presbyterian Hospital - New York
- Montefiore Medical Center - The Bronx
Maryland
- University of Maryland Medical Center/University of Maryland, Baltimore - Baltimore
- Johns Hopkins Medicine - Baltimore
Ohio
- Cleveland Clinic Foundation - Cleveland
- Ohio State University - Columbus
Georgia
- Emory University - Atlanta
Illinois
- Northwestern Memorial Hospital - Chicago
Missouri
- Washington University - Barnes Jewish Hospital - St Louis
Nebraska
- University of Nebraska Medical Center - Omaha
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 141 participants |
| Start Date | 2023-10-10 |
| Est. Completion | 2029-11 |
| Phase | NA |
What the registry record for NCT05881278 still lists
NCT05881278 is an interventional study that assigns participants to a tested intervention. The registered 141 participants enrollment target is mid-sized for trials with a published cap, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (93% lower).
The record links to 2 conditions, with Heart Failure appearing as the primary indexed condition, and to 1 intervention - of which Non-Ischemic Heart Preservation (NIHP) using the XVIVO Heart Preservation System (XHPS) is the first listed.
NCT05881278 names 20 study sites across 13 states, led by California, New York, Maryland.
Frequently Asked Questions
What is clinical trial NCT05881278 about?
NCT05881278 is a clinical study titled "XVIVO Heart Perfusion System (XHPS) With Supplemented XVIVO Heart Solution (SXHS)". The purpose of this study is to evaluate if Non-Ischemic Heart Preservation (NIHP) of extended criteria donor hearts using the XVIVO Heart Preservation System (XHPS) is a safe and effective way to preserve and transport hearts for transplantation.
What is the current status of trial NCT05881278?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 141 participants. The study started on 2023-10-10. Estimated completion is 2029-11.
What conditions does trial NCT05881278 study?
This clinical trial studies the following conditions: Heart Failure, Transplant; Failure, Heart.
What interventions are being tested in trial NCT05881278?
The interventions under investigation include: Non-Ischemic Heart Preservation (NIHP) using the XVIVO Heart Preservation System (XHPS) (DEVICE).
Who is sponsoring clinical trial NCT05881278?
This trial is sponsored by XVIVO Perfusion, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05881278 being conducted?
This trial has 20 study locations across California, Georgia, Illinois, Maryland, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05881278's enrollment target sits among peer trials
141 193rd of 397 higher than 205 of 397 other Heart Failure trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Heart Failure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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