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NCT05877885 · ClinicalTrials.gov registry record · NA
Targeting Network Dysfunction in Apathy of Late-life Depression Using Digital Therapeutics
A NA study of Major Depressive Disorder and Apathy, sponsored by AdventHealth.
- Recruiting
- Registry status
- NA
- Development phase
- 84
- Enrollment target
- 1
- Study location
NCT05877885 is a NA study of Major Depressive Disorder and Apathy that is actively recruiting participants, run by AdventHealth. The registered enrollment target is 84 participants, below the 377-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05877885, a NA study of Major Depressive Disorder and Apathy, is actively recruiting participants, sponsored by AdventHealth.
- RECRUITING
- Registry status
- NA
- Development phase
- 84 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this randomized controlled trial is to evaluate the potential of a customized digital cognitive training intervention to target aspects of brain function in apathy of late-life depression and reduce symptoms of apathy and related cognitive and behavioral deficits. The investigators hypothesize that 4 weeks of a customized digital cognitive training program will lead to changes in brain connectivity, apathy severity, and cognitive control performance.
Conditions Studied
Interventions
- BEHAVIORAL Targeted Cognitive Training Intervention
- BEHAVIORAL General Cognitive Training Intervention
Study Locations (1)
Florida
- AdventHealth Neuroscience Institute - Orlando
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 84 participants |
| Start Date | 2025-09-19 |
| Est. Completion | 2028-12-01 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05877885
The ClinicalTrials.gov registry entry for NCT05877885 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 84 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 377-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (78% lower). The listed sponsor is AdventHealth, which has 95 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Major Depressive Disorder appearing as the primary indexed condition, and to 2 interventions - of which Targeted Cognitive Training Intervention is the first listed.
NCT05877885 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.
Frequently Asked Questions
What is clinical trial NCT05877885 about?
NCT05877885 is a clinical study titled "Targeting Network Dysfunction in Apathy of Late-life Depression Using Digital Therapeutics". The goal of this randomized controlled trial is to evaluate the potential of a customized digital cognitive training intervention to target aspects of brain function in apathy of late-life depression and reduce symptoms of apathy and related cognitive and behavioral deficits. The investigators hypot...
What is the current status of trial NCT05877885?
This trial is currently recruiting. It is a NA study. The enrollment target is 84 participants. The study started on 2025-09-19. Estimated completion is 2028-12-01.
What conditions does trial NCT05877885 study?
This clinical trial studies the following conditions: Major Depressive Disorder, Apathy.
What interventions are being tested in trial NCT05877885?
The interventions under investigation include: Targeted Cognitive Training Intervention (BEHAVIORAL), General Cognitive Training Intervention (BEHAVIORAL).
Who is sponsoring clinical trial NCT05877885?
This trial is sponsored by AdventHealth, which has 95 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05877885 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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