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NCT05853068 · ClinicalTrials.gov registry record

Assessment of PaO2/FiO2 Ratio Pre and POst INTubation

A clinical trial of Acute Hypoxemic Respiratory Failure, sponsored by Dr. Negrin University Hospital.

Active
Registry status
400
Enrollment target
2
Study locations

NCT05853068 is a study of Acute Hypoxemic Respiratory Failure that is active but no longer recruiting, run by Dr. Negrin University Hospital. The registered enrollment target is 400 participants, below the 891-participant average among 5 other Acute Hypoxemic Respiratory Failure trials with a reported enrollment target (55% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT05853068, a study of Acute Hypoxemic Respiratory Failure, is active but no longer recruiting, sponsored by Dr. Negrin University Hospital.

ACTIVE NOT RECRUITING
Registry status
400 participants
Enrollment target
2
Study locations

Study Summary

We designed this study to dtermine whether invasive mechanical ventilation (MV) would have an impact on the reclassification of patients with acute hypoxemic respiratory failure (AHRF) -treated previously with non-invasive respiratory support- into categories of severity (mild, moderate, and severe). Our hypothesis is that the assessment of PaO2/FiO2 ratio on PEEP greater or equal to 5 cmH2O after intubation, in patients labeled as mild/moderate/severe AHRF while on non-invasive respiratory support, would identify that a marked proportion of patients would change the degree of severity after a brief period of invasive MV

Interventions

  • DEVICE Mechanical ventilation

Study Locations (2)

Illinois

  • Rush University Medical Center - Chicago

Las Palmas

  • Jesús Villar - Las Palmas de Gran Canaria

Trial Details

FieldValue
Enrollment Target 400 participants
Start Date 2023-04-29
Est. Completion 2025-11-30

Sponsor

Dr. Negrin University Hospital

1 total trials

What the Registry Record Tells You About NCT05853068

The ClinicalTrials.gov registry entry for NCT05853068 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 400 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 891-participant average among 5 other Acute Hypoxemic Respiratory Failure trials with a reported enrollment target (55% lower). The listed sponsor is Dr. Negrin University Hospital, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Acute Hypoxemic Respiratory Failure appearing as the primary indexed condition, and to 1 intervention - of which Mechanical ventilation is the first listed.

NCT05853068 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Illinois, Las Palmas.

Frequently Asked Questions

What is clinical trial NCT05853068 about?

NCT05853068 is a clinical study titled "Assessment of PaO2/FiO2 Ratio Pre and POst INTubation". We designed this study to dtermine whether invasive mechanical ventilation (MV) would have an impact on the reclassification of patients with acute hypoxemic respiratory failure (AHRF) -treated previously with non-invasive respiratory support- into categories of severity (mild, moderate, and severe)...

What is the current status of trial NCT05853068?

This trial is currently active not recruiting. The enrollment target is 400 participants. The study started on 2023-04-29. Estimated completion is 2025-11-30.

What conditions does trial NCT05853068 study?

This clinical trial studies the following conditions: Acute Hypoxemic Respiratory Failure.

What interventions are being tested in trial NCT05853068?

The interventions under investigation include: Mechanical ventilation (DEVICE).

Who is sponsoring clinical trial NCT05853068?

This trial is sponsored by Dr. Negrin University Hospital, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05853068 being conducted?

This trial has 2 study locations across Illinois, Las Palmas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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