Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05675345 · ClinicalTrials.gov registry record · NA
Physiological Effects of Continuous Negative External Pressure for Acute Hypoxemic Respiratory Failure
A NA study of Acute Hypoxemic Respiratory Failure, sponsored by Columbia University.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT05675345 is a NA study of Acute Hypoxemic Respiratory Failure that is actively recruiting participants, run by Columbia University. The registered enrollment target is 20 participants, below the 967-participant average among 5 other Acute Hypoxemic Respiratory Failure trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05675345, a NA study of Acute Hypoxemic Respiratory Failure, is actively recruiting participants, sponsored by Columbia University.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is being conducted to evaluate if wearing a non-invasive breathing support device over the chest/abdomen improves markers of breathing in patients with lung injury requiring high-flow oxygen. The breathing support device consists of a plastic shell that sits over the chest and abdomen and connects to a vacuum that helps the chest expand with breathing. This breathing support is known as continuous negative external pressure (CNEP). Study findings will help determine if this breathing support device might be useful for patients with acute hypoxemic respiratory failure (AHRF).
Conditions Studied
Interventions
- DEVICE HFNC only
- DEVICE HFNC + CNEP10
- DEVICE HFNC + CNEP20
- DEVICE HFNC + CNEP30
Study Locations (1)
New York
- Columbia University Irving Medical Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2024-02-28 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05675345
The ClinicalTrials.gov registry entry for NCT05675345 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 967-participant average among 5 other Acute Hypoxemic Respiratory Failure trials with a reported enrollment target (98% lower). The listed sponsor is Columbia University, which has 958 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Acute Hypoxemic Respiratory Failure appearing as the primary indexed condition, and to 4 interventions - of which HFNC only is the first listed.
NCT05675345 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.
Frequently Asked Questions
What is clinical trial NCT05675345 about?
NCT05675345 is a clinical study titled "Physiological Effects of Continuous Negative External Pressure for Acute Hypoxemic Respiratory Failure". This study is being conducted to evaluate if wearing a non-invasive breathing support device over the chest/abdomen improves markers of breathing in patients with lung injury requiring high-flow oxygen. The breathing support device consists of a plastic shell that sits over the chest and abdomen and...
What is the current status of trial NCT05675345?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2024-02-28. Estimated completion is 2026-12-31.
What conditions does trial NCT05675345 study?
This clinical trial studies the following conditions: Acute Hypoxemic Respiratory Failure.
What interventions are being tested in trial NCT05675345?
The interventions under investigation include: HFNC only (DEVICE), HFNC + CNEP10 (DEVICE), HFNC + CNEP20 (DEVICE), HFNC + CNEP30 (DEVICE).
Who is sponsoring clinical trial NCT05675345?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05675345 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Acute Hypoxemic Respiratory Failure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
The Effects of Music Therapy on Adult Patients Requiring Mechanical Ventilation in the ICU
RECRUITING · NA
-
ROX Index for the Timing of Intubation in Nasal High Flow
RECRUITING · NA
-
Optimizing Care in Critically Ill at UCHealth by Liberalizing the Target O2 in Mechanically-ventilated ICU Patients
RECRUITING · NA
-
Strategies for Anticoagulation During Venovenous ECMO
COMPLETED · NA
-
Assessment of PaO2/FiO2 Ratio Pre and POst INTubation
ACTIVE NOT RECRUITING
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.