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NCT05836324 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors
A Phase 1 study of Advanced Solid Tumors and Solid Tumors, sponsored by Incyte Corporation.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 408
- Enrollment target
- 20
- Study locations
NCT05836324: Recruiting Phase 1 study of Advanced Solid Tumors and Solid Tumors, sponsored by Incyte Corporation.
NCT05836324 is a Phase 1 study of Advanced Solid Tumors and Solid Tumors that is actively recruiting participants, run by Incyte Corporation. The registered enrollment target is 408 participants, above the 196-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (108% higher). The trial reports 20 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05836324, a Phase 1 study of Advanced Solid Tumors and Solid Tumors, is actively recruiting participants, sponsored by Incyte Corporation.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 408 participants
- Enrollment target
- 20
- Study locations
Study Summary
To evaluate the safety, tolerability, and DLTs and determine the MTD and/or RDE(s) of INCA33890 in participants with select advanced or metastatic solid tumors.
Conditions Studied
Interventions
- DRUG Cetuximab
- DRUG FOLFIRI
- DRUG FOLFOX
- DRUG bevacizumab
- DRUG INCA33890
Study Locations (20)
Other
- Rigshospitalet Uni of Hospital of Copenhagen - Copenhagen
- Herlev Og Gentofte Hospital - Herlev
- Odense University Hospital - Odense C
- Vejle Hospital - Vejle
- Centre Leon Berard - Lyon
- Institut Gustave Roussy - Villejuif
- Fondazione Irccs Istituto Nazionale Dei Tumori - Milan
- Irccs Istituto Clinico Humanitas - Rozzano
- Centro Ricerche Cliniche Di Verona - Verona
California
- The Angeles Clinic and Research Institute - Los Angeles
- Valkyrie Clinical Trials - Los Angeles
New York
- Nyu Langone Health - Long Island Hospital - Mineola
- Laura and Isaac Perlmutter Cancer Center - New York
Texas
- University of Texas Md Anderson Cancer Center - Houston
- South Texas Accelerated Research Therapeutics - San Antonio
Massachusetts
- Dana Farber Cancer Institute - Boston
Michigan
- Cancer and Hematology Centers of Western Michigan-Start Midwest - Grand Rapids
New Jersey
- Hackensack University Medical Center - Hackensack
Pennsylvania
- University of Pennsylvania - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 408 participants |
| Start Date | 2023-07-24 |
| Est. Completion | 2027-01-13 |
| Phase | Phase 1 |
What NCT05836324 shows while recruiting
NCT05836324 is an interventional study that assigns participants to a tested intervention. The registered 408 participants enrollment target is mid-sized for trials with a published cap, above the 196-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (108% higher).
The record links to 3 conditions, with Advanced Solid Tumors appearing as the primary indexed condition, and to 5 interventions - of which Cetuximab is the first listed.
NCT05836324 names 20 study sites across 9 states, led by Other, California, New York.
Frequently Asked Questions
What is clinical trial NCT05836324 about?
NCT05836324 is a clinical study titled "A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors". To evaluate the safety, tolerability, and DLTs and determine the MTD and/or RDE(s) of INCA33890 in participants with select advanced or metastatic solid tumors.
What is the current status of trial NCT05836324?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 408 participants. The study started on 2023-07-24. Estimated completion is 2027-01-13.
What conditions does trial NCT05836324 study?
This clinical trial studies the following conditions: Advanced Solid Tumors, Solid Tumors, Metastatic Solid Tumors.
What interventions are being tested in trial NCT05836324?
The interventions under investigation include: Cetuximab (DRUG), FOLFIRI (DRUG), FOLFOX (DRUG), bevacizumab (DRUG), INCA33890 (DRUG).
Who is sponsoring clinical trial NCT05836324?
This trial is sponsored by Incyte Corporation, which has 239 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05836324 being conducted?
This trial has 20 study locations across California, Massachusetts, Michigan, New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Advanced Solid Tumors
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05836324's enrollment target sits among peer trials
408 14th of 144 higher than 131 of 144 other Advanced Solid Tumors trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Advanced Solid Tumors trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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