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NCT05831579 · ClinicalTrials.gov registry record · NA
Palliative Spatially Fractionated (GRID) Radiotherapy Using Intensity Modulated Proton Therapy
A NA study of Metastatic Cancer and Unresectable Solid Tumor, sponsored by Washington University School of Medicine.
- Recruiting
- Registry status
- NA
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT05831579 is a NA study of Metastatic Cancer and Unresectable Solid Tumor that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 24 participants, below the 444-participant average among 109 other Metastatic Cancer trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05831579, a NA study of Metastatic Cancer and Unresectable Solid Tumor, is actively recruiting participants, sponsored by Washington University School of Medicine.
- RECRUITING
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
Spatially fractionated radiotherapy (SFRT or GRID) addresses some limitations of traditional stereotactic body radiation therapy by relying on beam collimation to create high-dose "peaks" and intervening low-dose "valleys" throughout the target volume. Standard palliative radiotherapy regimens provide limited durability of response, and there are challenges with delivery to large tumors or in previously irradiated fields. In this study, Proton GRID radiotherapy will be used to deliver three-fraction palliative radiotherapy to patients with tumors needing palliative radiation. The safety and efficacy of this approach will be assessed. It is hypothesized that GRID is highly effective, immunogenic, and associated with low rates of toxicity.
Conditions Studied
Interventions
- RADIATION Proton GRID Radiotherapy
Study Locations (1)
Missouri
- Washington University School of Medicine - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2023-05-12 |
| Est. Completion | 2027-06-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05831579
The ClinicalTrials.gov registry entry for NCT05831579 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 444-participant average among 109 other Metastatic Cancer trials with a reported enrollment target (95% lower). The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Metastatic Cancer appearing as the primary indexed condition, and to 1 intervention - of which Proton GRID Radiotherapy is the first listed.
NCT05831579 reports 1 study location spanning 1 distinct geographic area - top geographies include Missouri.
Frequently Asked Questions
What is clinical trial NCT05831579 about?
NCT05831579 is a clinical study titled "Palliative Spatially Fractionated (GRID) Radiotherapy Using Intensity Modulated Proton Therapy". Spatially fractionated radiotherapy (SFRT or GRID) addresses some limitations of traditional stereotactic body radiation therapy by relying on beam collimation to create high-dose "peaks" and intervening low-dose "valleys" throughout the target volume. Standard palliative radiotherapy regimens provi...
What is the current status of trial NCT05831579?
This trial is currently recruiting. It is a NA study. The enrollment target is 24 participants. The study started on 2023-05-12. Estimated completion is 2027-06-30.
What conditions does trial NCT05831579 study?
This clinical trial studies the following conditions: Metastatic Cancer, Unresectable Solid Tumor.
What interventions are being tested in trial NCT05831579?
The interventions under investigation include: Proton GRID Radiotherapy (RADIATION).
Who is sponsoring clinical trial NCT05831579?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05831579 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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