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NCT05818150 · ClinicalTrials.gov registry record · NA
GAE Using Embosphere Microspheres vs Corticosteroid Injections for Treatment of Symptomatic Knee OA (MOTION)
A NA study of Knee Osteoarthritis, sponsored by Merit Medical Systems.
- Active
- Registry status
- NA
- Development phase
- 264
- Enrollment target
- 20
- Study locations
NCT05818150: Active NA study of Knee Osteoarthritis, sponsored by Merit Medical Systems.
NCT05818150 is a NA study of Knee Osteoarthritis that is active but no longer recruiting, run by Merit Medical Systems. The registered enrollment target is 264 participants, below the 302-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (13% lower). The trial reports 20 study locations across 13 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05818150, a NA study of Knee Osteoarthritis, is active but no longer recruiting, sponsored by Merit Medical Systems.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 264 participants
- Enrollment target
- 20
- Study locations
Study Summary
This multicenter, prospective, interventional trial is designed to assess the outcome of subjects with symptomatic knee osteoarthritis (OA) that are randomized to treatment with either genicular artery embolization (GAE) using Embosphere Microspheres or steroid injection over a period of 24 months.
Primary Outcome
Clinical Success defined as ≥50% improvement in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain Subscale from baseline to 6 months without the need for additional intervention.
Conditions Studied
Interventions
- DRUG Corticosteroid injection
- DEVICE Embosphere Microspheres
Study Locations (20)
New York
- Northwell Health - Manhasset
- Weill Cornell Medicine - New York
- Atlas Interventional - Williamsville
District of Columbia
- Georgetown University Medical Center - Washington D.C.
- MedStar Washington Hospital Center - Washington D.C.
Georgia
- Emory University School of Medicine - Atlanta
- Biotech Clinical Research/ Georgia Vascular Institute - College Park
New Jersey
- Atlantic Medical Imaging - Galloway
- Rutgers Health - Newark
North Carolina
- Prostate Centers USA - Raleigh
- Sunrise Vascular Center - Sanford
Virginia
- Prostate Centers USA - Falls Church
- Prostate Centers USA - Leesburg
California
- Memorial Care Long Beach Medical Center - Long Beach
Illinois
- Northwestern University - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 264 participants |
| Start Date | 2024-01-16 |
| Est. Completion | 2027-10 |
| Phase | NA |
What the registry record for NCT05818150 still lists
NCT05818150 is an interventional study that assigns participants to a tested intervention. The registered 264 participants enrollment target is mid-sized for trials with a published cap, below the 302-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (13% lower).
The record links to 1 condition, with Knee Osteoarthritis appearing as the primary indexed condition, and to 2 interventions - of which Corticosteroid injection is the first listed.
NCT05818150 names 20 study sites across 13 states, led by New York, District of Columbia, Georgia.
Frequently Asked Questions
What is clinical trial NCT05818150 about?
NCT05818150 is a clinical study titled "GAE Using Embosphere Microspheres vs Corticosteroid Injections for Treatment of Symptomatic Knee OA (MOTION)". This multicenter, prospective, interventional trial is designed to assess the outcome of subjects with symptomatic knee osteoarthritis (OA) that are randomized to treatment with either genicular artery embolization (GAE) using Embosphere Microspheres or steroid injection over a period of 24 months.
What is the current status of trial NCT05818150?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 264 participants. The study started on 2024-01-16. Estimated completion is 2027-10.
What conditions does trial NCT05818150 study?
This clinical trial studies the following conditions: Knee Osteoarthritis.
What interventions are being tested in trial NCT05818150?
The interventions under investigation include: Corticosteroid injection (DRUG), Embosphere Microspheres (DEVICE).
Who is sponsoring clinical trial NCT05818150?
This trial is sponsored by Merit Medical Systems, which has 18 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05818150 being conducted?
This trial has 20 study locations across California, District of Columbia, Georgia, Illinois, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Knee Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05818150's enrollment target sits among peer trials
264 18th of 101 higher than 84 of 101 other Knee Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Knee Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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