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NCT05795114 · ClinicalTrials.gov registry record · NA
Perinatal Depression and Adverse Childhood Experiences: Prevention Trial
A NA study of Perinatal Depression, sponsored by Northwestern University.
- Recruiting
- Registry status
- NA
- Development phase
- 76
- Enrollment target
- 1
- Study location
NCT05795114: Recruiting NA study of Perinatal Depression, sponsored by Northwestern University.
NCT05795114 is a NA study of Perinatal Depression that is actively recruiting participants, run by Northwestern University. The registered enrollment target is 76 participants, below the 473-participant average among 12 other Perinatal Depression trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05795114, a NA study of Perinatal Depression, is actively recruiting participants, sponsored by Northwestern University.
- RECRUITING
- Registry status
- NA
- Development phase
- 76 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to evaluate the impact of ROSE in individuals with adverse childhood experiences. The main question it aims to answer is, compared to enhanced treatment as usual, does the delivery of ROSE within a collaborative care model improve depressive symptom trajectories and prevent the development of perinatal depression. Participants will be randomized to either enhanced treatment as usual or the ROSE intervention, delivered by a care manager within a perinatal collaborative care program. They will complete self-reported surveys of their depression symptoms every 4 weeks to inform their symptom trajectories. They will also complete clinical interviews to establish any incident diagnoses of a major depressive episode.
Primary Outcome
Depression symptom trajectories will be measured via Patient Health Questionnaire-9 (PHQ-9) screens administered
Conditions Studied
Interventions
- BEHAVIORAL Reach Out, Stand Strong, Essentials for New Mothers (ROSE) Program
Study Locations (1)
Illinois
- Northwestern Medicine - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 76 participants |
| Start Date | 2023-07-20 |
| Est. Completion | 2026-01-31 |
| Phase | NA |
What NCT05795114 shows while recruiting
NCT05795114 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 76 participants, a relatively small participant target, below the 473-participant average among 12 other Perinatal Depression trials with a reported enrollment target (84% lower).
The record links to 1 condition, with Perinatal Depression appearing as the primary indexed condition, and to 1 intervention - of which Reach Out, Stand Strong, Essentials for New Mothers (ROSE) Program is the first listed.
NCT05795114 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT05795114 about?
NCT05795114 is a clinical study titled "Perinatal Depression and Adverse Childhood Experiences: Prevention Trial". The goal of this clinical trial is to evaluate the impact of ROSE in individuals with adverse childhood experiences. The main question it aims to answer is, compared to enhanced treatment as usual, does the delivery of ROSE within a collaborative care model improve depressive symptom trajectories an...
What is the current status of trial NCT05795114?
This trial is currently recruiting. It is a NA study. The enrollment target is 76 participants. The study started on 2023-07-20. Estimated completion is 2026-01-31.
What conditions does trial NCT05795114 study?
This clinical trial studies the following conditions: Perinatal Depression.
What interventions are being tested in trial NCT05795114?
The interventions under investigation include: Reach Out, Stand Strong, Essentials for New Mothers (ROSE) Program (BEHAVIORAL).
Who is sponsoring clinical trial NCT05795114?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05795114 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Perinatal Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05795114's enrollment target sits among peer trials
76 11th of 12 higher than 2 of 12 other Perinatal Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Perinatal Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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