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Perinatal Depression clinical trials
Every US clinical trial registered for Perinatal Depression — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
13 US clinical trials · 7 currently recruiting
The research picture
Perinatal Depression has 13 registered US clinical trials, 7 of them open to new participants right now — about 54% of the total.
- 7
- recruiting participants now
- 54%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Northwestern University
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Pathways to Perinatal Mental Health Equity
University of Massachusetts, Worcester
NCT06790641
Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women
Cedars-Sinai Medical Center
NCT05552053
Maternal Mental Health Access - MaMa
University of Utah
NCT06049433
Testing "Doula Link", a Multi-Component Intervention to Improve Perinatal Mental Health
Beth Israel Deaconess Medical Center
NCT07217561
Perinatal Depression and Adverse Childhood Experiences: Prevention Trial
Northwestern University
NCT05795114
Feasibility and Acceptability of a Novel Cognitive Behavioral Skills Mobile App for Pregnant and Postpartum Individuals
Weill Medical College of Cornell University
NCT05897619
Accelerated TMS for Perinatal Depression
Brigham and Women's Hospital
NCT06968390
The DC Mother-Infant Behavioral Wellness Program
Children's National Research Institute
NCT05345834
mHealth Mindfulness Intervention for Pregnant Black and Latina Women at Risk of Postpartum Depression
Kaiser Permanente
NCT05186272
Elevating Voices, Addressing Depression, Toxic Stress and Equity in Group Prenatal Care
Washington University School of Medicine
NCT04838210
Scaling Up Maternal Mental Healthcare by Increasing Access to Treatment (SUMMIT)
Mount Sinai Hospital, Canada
NCT04153864
Comparing the Effectiveness of Clinicians and Paraprofessionals to Reduce Disparities in Perinatal Depression
Northwestern University
NCT02979444
Peer Mentor Texting
University of Washington
NCT07380061
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 1 |
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Perinatal Depression Trial Landscape
ClinicalTrials.gov lists 13 US studies indexed under Perinatal Depression, and 7 of those are currently open to recruitment — roughly 54% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Perinatal Depression shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 1 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Perinatal Depression is led by Northwestern University with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 13 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Perinatal Depression?
PlainTrial tracks 13 US clinical trials for Perinatal Depression, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Perinatal Depression?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.