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The Efficacy and Safety of TLL018 in Moderate-to-severe Plaque Psoriasis
NCT05772520 · View on ClinicalTrials.gov ↗
Study Summary
This is a Phase 2, multicenter, randomized, double-blinded, parallel dose group, placebo-controlled, dose-ranging study to evaluate the efficacy and safety of 2 doses of TLL018 as therapy in approximately 90 participants with moderate-to-severe PP.
Conditions Studied
Interventions
- DRUG TLL018 tablets
Study Locations (20)
Florida
- Life Clinical Trials — Coral Springs
- Palm Beach — DeLand
- D&H Doral Research Center LLC — Doral
- Sweet Hope Research Specialty, Inc — Hialeah
- CNS - Jacksonville — Jacksonville
- CNS - Orlando SODO — Jacksonville
- Altus Research — Lake Worth
- Anchor Medical Research, LLC (Core Clinical Trials) — Miami
- Reserka Research — Miami
- ForCare Medical (CenExcel) — Tampa
California
- Moy, Fincher, Chipps — Beverly Hills
- Metropolis Derm — Los Angeles
- Amicis Research Center — Northridge
- Integrative Skin — Sacramento
- Skin Surgical — San Diego
Alabama
- Cahaba — Birmingham
Iowa
- Integrated Clinical Trial Services, Inc — Des Moines
Louisiana
- IMA Clinical Research — Monroe
Maryland
- Lawrence Green — Rockville
Massachusetts
- Metro Boston — Brighton
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 82 participants |
| Start Date | 2023-01-19 |
| Est. Completion | 2024-12-23 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05772520
The ClinicalTrials.gov registry entry for NCT05772520 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 82 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Hangzhou Highlightll Pharmaceutical Co., which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Plaque Psoriasis appearing as the primary indexed condition, and to 1 intervention — of which TLL018 tablets is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05772520 reports 20 study locations spanning 7 distinct geographic areas — top geographies include Florida, California, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05772520 about?
NCT05772520 is a clinical study titled "The Efficacy and Safety of TLL018 in Moderate-to-severe Plaque Psoriasis". This is a Phase 2, multicenter, randomized, double-blinded, parallel dose group, placebo-controlled, dose-ranging study to evaluate the efficacy and safety of 2 doses of TLL018 as therapy in approximately 90 participants with moderate-to-severe PP.
What is the current status of trial NCT05772520?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 82 participants. The study started on 2023-01-19. Estimated completion is 2024-12-23.
What conditions does trial NCT05772520 study?
This clinical trial studies the following conditions: Plaque Psoriasis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05772520?
The interventions under investigation include: TLL018 tablets (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05772520?
This trial is sponsored by Hangzhou Highlightll Pharmaceutical Co., which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05772520 being conducted?
This trial has 20 study locations across Alabama, California, Florida, Iowa, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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