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NCT07090330 · ClinicalTrials.gov registry record · Phase 2
ORKA-001 Versus Placebo in Patients With Moderate-to-Severe Plaque Psoriasis
A Phase 2 study of Plaque Psoriasis, sponsored by Oruka Therapeutics.
- Active
- Registry status
- Phase 2
- Development phase
- 80
- Enrollment target
- 20
- Study locations
NCT07090330 is a Phase 2 study of Plaque Psoriasis that is active but no longer recruiting, run by Oruka Therapeutics. The registered enrollment target is 80 participants, below the 414-participant average among 45 other Plaque Psoriasis trials with a reported enrollment target (81% lower). The trial reports 20 study locations across 14 states.
The verdict
NCT07090330, a Phase 2 study of Plaque Psoriasis, is active but no longer recruiting, sponsored by Oruka Therapeutics.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 80 participants
- Enrollment target
- 20
- Study locations
Study Summary
This is a multicenter, randomized, double-blinded, placebo-controlled, proof-of-concept study to evaluate the efficacy, safety, tolerability, and pharmacokinetics of ORKA-001 in adult participants with moderate-to-severe plaque psoriasis.
Conditions Studied
Interventions
- OTHER Placebo
- DRUG ORKA-001 Induction Dose
- DRUG ORKA-001 Maintenance Dose
Study Locations (20)
California
- Oruka Therapeutics Investigative Site - Fountain Valley
- Oruka Therapeutics Investigative Site - Los Angeles
- Oruka Therapeutics Investigative Site - San Diego
- Oruka Therapeutics Investigative Site - Santa Ana
- Oruka Therapeutics Investigative Site - Santa Monica
New York
- Oruka Therapeutics Investigative Site - New York
- Oruka Therapeutics Investigative Site - New York
Alberta
- Oruka Therapeutics Investigative Site - Edmonton
- Oruka Therapeutics Investigative Site - Edmonton
Connecticut
- Oruka Therapeutics Investigative Site - Cromwell
Florida
- Oruka Therapeutics Investigative Site - Coral Gables
Illinois
- Oruka Therapeutics Investigative Site - Rolling Meadows
Kentucky
- Oruka Therapeutics Investigative Site - Bowling Green
Maryland
- Oruka Therapeutics Investigative Site - Rockville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2025-07-18 |
| Est. Completion | 2027-05 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07090330
The ClinicalTrials.gov registry entry for NCT07090330 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 414-participant average among 45 other Plaque Psoriasis trials with a reported enrollment target (81% lower). The listed sponsor is Oruka Therapeutics, which has 4 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Plaque Psoriasis appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT07090330 reports 20 study locations spanning 14 distinct geographic areas - top geographies include California, New York, Alberta.
Frequently Asked Questions
What is clinical trial NCT07090330 about?
NCT07090330 is a clinical study titled "ORKA-001 Versus Placebo in Patients With Moderate-to-Severe Plaque Psoriasis". This is a multicenter, randomized, double-blinded, placebo-controlled, proof-of-concept study to evaluate the efficacy, safety, tolerability, and pharmacokinetics of ORKA-001 in adult participants with moderate-to-severe plaque psoriasis.
What is the current status of trial NCT07090330?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 80 participants. The study started on 2025-07-18. Estimated completion is 2027-05.
What conditions does trial NCT07090330 study?
This clinical trial studies the following conditions: Plaque Psoriasis.
What interventions are being tested in trial NCT07090330?
The interventions under investigation include: Placebo (OTHER), ORKA-001 Induction Dose (DRUG), ORKA-001 Maintenance Dose (DRUG).
Who is sponsoring clinical trial NCT07090330?
This trial is sponsored by Oruka Therapeutics, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07090330 being conducted?
This trial has 20 study locations across California, Connecticut, Florida, Illinois, Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Read our methodology - how this data is sourced, computed, and verified.
Related
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