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NCT05732207 · ClinicalTrials.gov registry record · NA
Cerebellar Involvement in Alcohol Use Disorder (AUD)
A NA study of Alcohol Use Disorder, sponsored by Johns Hopkins University.
- Recruiting
- Registry status
- NA
- Development phase
- 122
- Enrollment target
- 1
- Study location
NCT05732207: Recruiting NA study of Alcohol Use Disorder, sponsored by Johns Hopkins University.
NCT05732207 is a NA study of Alcohol Use Disorder that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 122 participants, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (63% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05732207, a NA study of Alcohol Use Disorder, is actively recruiting participants, sponsored by Johns Hopkins University.
- RECRUITING
- Registry status
- NA
- Development phase
- 122 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this observational and interventional study is to better understand the involvement of the cerebellum in the brain reward system in persons with alcohol use disorder (AUD). The main questions it aims to answer are: 1. What is the nature of cerebellar input to the ventral tegmental area (VTA) in the brain reward system, and how is it perturbed in AUD? 2. What is the relationship between measures of cerebellar integrity and magnitude of reward activation to alcohol-related cues in cerebellar, VTA and other brain reward structures? 3. What is the therapeutic potential of cerebellar transcranial direct current stimulation (tDCS) for modulating alcohol cue reactivity, associated alcohol craving, and cerebellar - VTA functional connectivity in the brain reward system? Persons with AUD will be compared with healthy control participants.
Primary Outcome
Participants will view blocks of pictures of alcohol and non-alcohol beverages, as well as control pictures and periods of rest. Participant rating of alcohol craving are obtained during the picture presentations using one of 5 buttons placed under their fingers, where 5 (thumb) = Extreme, 4=Severe, 3=Moderate, 2=Mild, 1=None
Conditions Studied
Interventions
- PROCEDURE cerebellar transcranial direct current stimulation
Study Locations (1)
Maryland
- Johns Hopkins University School of Medicine - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 122 participants |
| Start Date | 2023-10-12 |
| Est. Completion | 2027-09 |
| Phase | NA |
What NCT05732207 shows while recruiting
NCT05732207 is an interventional study that assigns participants to a tested intervention. The registered 122 participants enrollment target is mid-sized for trials with a published cap, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (63% lower).
The record links to 1 condition, with Alcohol Use Disorder appearing as the primary indexed condition, and to 1 intervention - of which cerebellar transcranial direct current stimulation is the first listed.
NCT05732207 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT05732207 about?
NCT05732207 is a clinical study titled "Cerebellar Involvement in Alcohol Use Disorder (AUD)". The goal of this observational and interventional study is to better understand the involvement of the cerebellum in the brain reward system in persons with alcohol use disorder (AUD). The main questions it aims to answer are: 1. What is the nature of cerebellar input to the ventral tegmental area ...
What is the current status of trial NCT05732207?
This trial is currently recruiting. It is a NA study. The enrollment target is 122 participants. The study started on 2023-10-12. Estimated completion is 2027-09.
What conditions does trial NCT05732207 study?
This clinical trial studies the following conditions: Alcohol Use Disorder.
What interventions are being tested in trial NCT05732207?
The interventions under investigation include: cerebellar transcranial direct current stimulation (PROCEDURE).
Who is sponsoring clinical trial NCT05732207?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05732207 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alcohol Use Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05732207's enrollment target sits among peer trials
122 75th of 184 higher than 110 of 184 other Alcohol Use Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alcohol Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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