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NCT05671861 · ClinicalTrials.gov registry record · NA

Evaluating a Low-Cost Therapeutic Device in Managing Head and Neck Cancer Patients With Radiation-Related Trismus

A NA study of Head and Neck Cancer and Trismus, sponsored by University of California, San Francisco.

Active
Registry status
NA
Development phase
35
Enrollment target
1
Study location

NCT05671861 is a NA study of Head and Neck Cancer and Trismus that is active but no longer recruiting, run by University of California, San Francisco. The registered enrollment target is 35 participants, below the 261-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05671861, a NA study of Head and Neck Cancer and Trismus, is active but no longer recruiting, sponsored by University of California, San Francisco.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
35 participants
Enrollment target
1
Study location

Study Summary

This trial evaluates how well a new therapeutic device works in managing trismus in patients who received radiation treatment for head and neck cancer. Radiation therapy is a common form of treatment in patients with head and neck cancers. However, changes to surrounding tissue following radiation therapy may lead to trismus, an inability to open the mouth fully. This can create significant functional impairment leading to malnutrition due to impaired chewing, risk of dental infections due to impaired oral hygiene, difficulty with speech, and decreased health-related quality of life. Exercise therapy is the mainstay of treatment for post-radiation trismus to help improve mobility and flexibility and increase range of mouth opening. This new device is non-invasive and is similar to other jaw stretching devices where a mouthpiece is placed between the teeth and a hand-lever is used to spread open the upper and lower jaw. However, it will also have additional sensors to measure pressure exerted by the hands and jaw as well as the distance to open the mouth which could help guide therapy. This study may help doctors customize a device to patient-specific needs, provide real-time feedback, and encourage compliance for trismus exercise therapy.

Interventions

  • OTHER Questionnaires
  • OTHER Mobile Application
  • DEVICE Trismus Device Prototype

Study Locations (1)

California

  • University of California, San Francisco - San Francisco

Trial Details

FieldValue
Enrollment Target 35 participants
Start Date 2023-04-27
Est. Completion 2028-03-31
Phase NA

What the Registry Record Tells You About NCT05671861

The ClinicalTrials.gov registry entry for NCT05671861 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 35 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 261-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (87% lower). The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Head and Neck Cancer appearing as the primary indexed condition, and to 3 interventions - of which Questionnaires is the first listed.

NCT05671861 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT05671861 about?

NCT05671861 is a clinical study titled "Evaluating a Low-Cost Therapeutic Device in Managing Head and Neck Cancer Patients With Radiation-Related Trismus". This trial evaluates how well a new therapeutic device works in managing trismus in patients who received radiation treatment for head and neck cancer. Radiation therapy is a common form of treatment in patients with head and neck cancers. However, changes to surrounding tissue following radiation t...

What is the current status of trial NCT05671861?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 35 participants. The study started on 2023-04-27. Estimated completion is 2028-03-31.

What conditions does trial NCT05671861 study?

This clinical trial studies the following conditions: Head and Neck Cancer, Trismus.

What interventions are being tested in trial NCT05671861?

The interventions under investigation include: Questionnaires (OTHER), Mobile Application (OTHER), Trismus Device Prototype (DEVICE).

Who is sponsoring clinical trial NCT05671861?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05671861 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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