Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 2

Evaluation of Sonelokimab for the Treatment of Patients With Active Psoriatic Arthritis

NCT05640245 · View on ClinicalTrials.gov ↗

Study Summary

This is a study to demonstrate the clinical efficacy and safety of the nanobody® sonelokimab administered subcutaneously (sc) compared with placebo in the treatment of adult participants with active psoriatic arthritis. The study includes adalimumab treatment as an active reference arm.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Adalimumab
  • DRUG Sonelokimab

Study Locations (20)

Other

  • Clinical Site — Pleven
  • Clinical Site — Pleven
  • Clinical Site — Plovdiv
  • Clinical Site — Plovdiv
  • Clinical Site — Rousse
  • Clinical Site — Sofia
  • Clinical Site — Stara Zagora
  • Clinical Site — Varna
  • Clinical Site — Ostrava
  • Clinical Site — Tallinn
  • Clinical Site — Tartu
  • Clinical Site — Hamburg
  • Clinical Site — Herne
  • Clinical Site — Budapest
  • Clinical Site — Budapest
  • Clinical Site — Budapest
  • Clinical Site — Szentes
  • Clinical Site — Székesfehérvár

California

  • Clinical Site — Rancho Mirage

Pennsylvania

  • Clinical Site — Duncansville

Trial Details

FieldValue
Enrollment Target 207 participants
Start Date 2022-12-13
Est. Completion 2024-01-15
Phase Phase 2

Sponsor

MoonLake Immunotherapeutics

33 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05640245

The ClinicalTrials.gov registry entry for NCT05640245 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 207 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is MoonLake Immunotherapeutics, which has 33 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Arthritis, Psoriatic appearing as the primary indexed condition, and to 3 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05640245 reports 20 study locations spanning 3 distinct geographic areas — top geographies include Other, California, Pennsylvania. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05640245 about?

NCT05640245 is a clinical study titled "Evaluation of Sonelokimab for the Treatment of Patients With Active Psoriatic Arthritis". This is a study to demonstrate the clinical efficacy and safety of the nanobody® sonelokimab administered subcutaneously (sc) compared with placebo in the treatment of adult participants with active psoriatic arthritis. The study includes adalimumab treatment as an active reference arm.

What is the current status of trial NCT05640245?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 207 participants. The study started on 2022-12-13. Estimated completion is 2024-01-15.

What conditions does trial NCT05640245 study?

This clinical trial studies the following conditions: Arthritis, Psoriatic. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05640245?

The interventions under investigation include: Placebo (DRUG), Adalimumab (DRUG), Sonelokimab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05640245?

This trial is sponsored by MoonLake Immunotherapeutics, which has 33 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05640245 being conducted?

This trial has 20 study locations across California, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial