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RECRUITING Phase 2

A Study to Evaluate the Efficacy and Safety of JNJ-88545223 for the Treatment of Participants With Active Psoriatic Arthritis

NCT07321873 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to evaluate how well the study drug JNJ-88545223 works compared with a placebo (an inactive substance) in adults with active psoriatic arthritis (PsA). The study aims to see whether treatment with JNJ-88545223 can help reduce the signs and symptoms of PsA and improve joint and skin health.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG JNJ-88545223

Study Locations (19)

Other

  • Peking University People's Hospital — Beijing
  • Ningbo medical center lihuili hospital — Ningbo
  • Hospital of the University of Occupational and Environmental Health — Kitakyushu-shi
  • Osaka Metropolitan University Hospital — Osaka
  • Sanuki Municipal Hospital — Sanuki

Florida

  • American Research, LLC — Cutler Bay
  • Innovation Medical Research Center — Palmetto Bay
  • Clinical Research of West Florida — Tampa
  • Conquest Research — Winter Park

California

  • Newport Huntington Medical Group — Huntington Beach
  • Rheumatology Center of San Diego — San Diego

Arkansas

  • Unity Health-White County Medical Center — Searcy

Georgia

  • Atlanta Research Center for Rheumatology — Marietta

Illinois

  • Willow Rheumatology and Wellness PLLC — Willowbrook

Indiana

  • Qualmedica Research — Evansville

North Carolina

  • Joint and Muscle Research Institute — Charlotte

Trial Details

FieldValue
Enrollment Target 240 participants
Start Date 2026-01-15
Est. Completion 2027-08-02
Phase Phase 2

Sponsor

Janssen Research & Development

442 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07321873

The ClinicalTrials.gov registry entry for NCT07321873 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 240 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Janssen Research & Development, which has 442 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Arthritis, Psoriatic appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07321873 reports 19 study locations spanning 11 distinct geographic areas — top geographies include Other, Florida, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07321873 about?

NCT07321873 is a clinical study titled "A Study to Evaluate the Efficacy and Safety of JNJ-88545223 for the Treatment of Participants With Active Psoriatic Arthritis". The purpose of this study is to evaluate how well the study drug JNJ-88545223 works compared with a placebo (an inactive substance) in adults with active psoriatic arthritis (PsA). The study aims to see whether treatment with JNJ-88545223 can help reduce the signs and symptoms of PsA and improve joi...

What is the current status of trial NCT07321873?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 240 participants. The study started on 2026-01-15. Estimated completion is 2027-08-02.

What conditions does trial NCT07321873 study?

This clinical trial studies the following conditions: Arthritis, Psoriatic. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07321873?

The interventions under investigation include: Placebo (DRUG), JNJ-88545223 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07321873?

This trial is sponsored by Janssen Research & Development, which has 442 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07321873 being conducted?

This trial has 19 study locations across Arkansas, California, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial