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Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response
NCT06641089 · View on ClinicalTrials.gov ↗
Study Summary
This is a study to confirm the clinical efficacy and safety of sonelokimab compared with placebo in the treatment of adults with active psoriatic arthritis who have had a previous inadequate response or intolerance to anti-tumor necrosis factor (TNF)α therapy.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Sonelokimab
- DRUG Risankizumab
Study Locations (20)
Arizona
- Clinical Site — Avondale
- Clinical Site — Chandler
- Clinical Site — Flagstaff
- Clinical Site — Mesa
- Clinical Site — Phoenix
- Clinical Site — Scottsdale
- Clinical Site — Tucson
California
- Clinical Site — La Jolla
- Clinical Site — Pomona
- Clinical Site — San Diego
- Clinical Site — Santa Monica
- Clinical Site — Thousand Oaks
- Clinical Site — Upland
Florida
- Clinical Site — Avon Park
- Clinical Site — Clearwater
- Clinical Site — Hialeah
- Clinical Site — Miami Gardens
- Clinical Site — Tampa
- Clinical Site — Zephyrhills
Arkansas
- Clinical Site — Jonesboro
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 600 participants |
| Start Date | 2024-10-15 |
| Est. Completion | 2027-01-15 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06641089
The ClinicalTrials.gov registry entry for NCT06641089 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 600 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is MoonLake Immunotherapeutics, which has 33 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Arthritis, Psoriatic appearing as the primary indexed condition, and to 3 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06641089 reports 20 study locations spanning 4 distinct geographic areas — top geographies include Arizona, California, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06641089 about?
NCT06641089 is a clinical study titled "Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response". This is a study to confirm the clinical efficacy and safety of sonelokimab compared with placebo in the treatment of adults with active psoriatic arthritis who have had a previous inadequate response or intolerance to anti-tumor necrosis factor (TNF)α therapy.
What is the current status of trial NCT06641089?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 600 participants. The study started on 2024-10-15. Estimated completion is 2027-01-15.
What conditions does trial NCT06641089 study?
This clinical trial studies the following conditions: Arthritis, Psoriatic. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06641089?
The interventions under investigation include: Placebo (DRUG), Sonelokimab (DRUG), Risankizumab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06641089?
This trial is sponsored by MoonLake Immunotherapeutics, which has 33 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06641089 being conducted?
This trial has 20 study locations across Arizona, Arkansas, California, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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