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NCT05630677 · ClinicalTrials.gov registry record · Phase 1

A Study to Compare Bioavailability of AZD5055 Film-coated Tablet With AZD5055 Oral Suspension and to Assess the Effect of Food and an Acid Reducing Agent on Pharmacokinetics (PK) of AZD5055 in Healthy Subjects.

A Phase 1 study, sponsored by AstraZeneca.

Completed
Registry status
Phase 1
Development phase
21
Enrollment target

NCT05630677 is a Phase 1 study that has completed, run by AstraZeneca. The registered enrollment target is 21 participants.

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The verdict

NCT05630677, a Phase 1 study, has completed, sponsored by AstraZeneca.

COMPLETED
Registry status
Phase 1
Development phase
21 participants
Enrollment target

Study Summary

This study will estimate the relative bioavailability of AZD5055 film-coated tablet as compared to AZD5055 oral suspension. The study will also assess the absolute bioavailabilty of AZD5055 and the effect of food and an acid reducing agent, rabeprazole, on the PK of AZD5055 film-coated tablets when given with food (fed state) or without food (fasted state).

Interventions

  • DRUG AZD5055 solution for infusion
  • DRUG AZD5055 oral suspension
  • DRUG AZD5055 film-coated tablet
  • DRUG Rabeprazole, Delayed-release tablet

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2022-11-04
Est. Completion 2023-02-09
Phase Phase 1

Sponsor

AstraZeneca

1,285 total trials

What the Registry Record Tells You About NCT05630677

The ClinicalTrials.gov registry entry for NCT05630677 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 21 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which AZD5055 solution for infusion is the first listed.

NCT05630677 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05630677 about?

NCT05630677 is a clinical study titled "A Study to Compare Bioavailability of AZD5055 Film-coated Tablet With AZD5055 Oral Suspension and to Assess the Effect of Food and an Acid Reducing Agent on Pharmacokinetics (PK) of AZD5055 in Healthy Subjects.". This study will estimate the relative bioavailability of AZD5055 film-coated tablet as compared to AZD5055 oral suspension. The study will also assess the absolute bioavailabilty of AZD5055 and the effect of food and an acid reducing agent, rabeprazole, on the PK of AZD5055 film-coated tablets when ...

What is the current status of trial NCT05630677?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 21 participants. The study started on 2022-11-04. Estimated completion is 2023-02-09.

What interventions are being tested in trial NCT05630677?

The interventions under investigation include: AZD5055 solution for infusion (DRUG), AZD5055 oral suspension (DRUG), AZD5055 film-coated tablet (DRUG), Rabeprazole, Delayed-release tablet (DRUG).

Who is sponsoring clinical trial NCT05630677?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.