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NCT05572671 · ClinicalTrials.gov registry record · NA
Linking Brain Network Dynamics to Imminent Smoking Lapse Risk and Behavior
A NA study of Smoking and Tobacco Use, sponsored by Penn State University.
- Recruiting
- Registry status
- NA
- Development phase
- 150
- Enrollment target
- 1
- Study location
NCT05572671: Recruiting NA study of Smoking and Tobacco Use, sponsored by Penn State University.
NCT05572671 is a NA study of Smoking and Tobacco Use that is actively recruiting participants, run by Penn State University. The registered enrollment target is 150 participants, below the 454-participant average among 123 other Smoking trials with a reported enrollment target (67% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05572671, a NA study of Smoking and Tobacco Use, is actively recruiting participants, sponsored by Penn State University.
- RECRUITING
- Registry status
- NA
- Development phase
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
Most attempts to quit smoking end in relapse, or a return to regular smoking. One of the biggest threats to cessation is a lapse (i.e., any cigarette use during a quit attempt). Thus, characterizing why lapses occur is essential to understanding and preventing smoking relapse. Functional magnetic resonance imaging (fMRI) is a promising method for characterizing the psychological processes that lead to smoking lapses because it provides a way to measures patterns of brain activity thought to reflect relevant mental processes as they change over time. However, methodological issues have hindered the ability to capitalize on this potential and prevented an understanding of how brain activity and corresponding psychological processes unfold in the critical moments that immediately precede a smoking lapse. The proposed project will address this knowledge gap using a novel fMRI paradigm adapted from a well-validated behavioral lapse task. The goals of the project are to characterize changes in brain activity that lead up to a lapse and to investigate how these changes are related to concurrent affect and subsequent cigarette use.
Primary Outcome
Blood-oxygen-level dependent (BOLD) signal measured using functional magnetic resonance imaging
Conditions Studied
Interventions
- BEHAVIORAL Laboratory task modeling smoking lapse behavior
Study Locations (1)
Pennsylvania
- The Pennsylvania State University - University Park
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2023-04-04 |
| Est. Completion | 2027-08 |
| Phase | NA |
What NCT05572671 shows while recruiting
NCT05572671 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 454-participant average among 123 other Smoking trials with a reported enrollment target (67% lower).
The record links to 2 conditions, with Smoking appearing as the primary indexed condition, and to 1 intervention - of which Laboratory task modeling smoking lapse behavior is the first listed.
NCT05572671 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05572671 about?
NCT05572671 is a clinical study titled "Linking Brain Network Dynamics to Imminent Smoking Lapse Risk and Behavior". Most attempts to quit smoking end in relapse, or a return to regular smoking. One of the biggest threats to cessation is a lapse (i.e., any cigarette use during a quit attempt). Thus, characterizing why lapses occur is essential to understanding and preventing smoking relapse. Functional magnetic re...
What is the current status of trial NCT05572671?
This trial is currently recruiting. It is a NA study. The enrollment target is 150 participants. The study started on 2023-04-04. Estimated completion is 2027-08.
What conditions does trial NCT05572671 study?
This clinical trial studies the following conditions: Smoking, Tobacco Use.
What interventions are being tested in trial NCT05572671?
The interventions under investigation include: Laboratory task modeling smoking lapse behavior (BEHAVIORAL).
Who is sponsoring clinical trial NCT05572671?
This trial is sponsored by Penn State University, which has 219 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05572671 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Smoking
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05572671's enrollment target sits among peer trials
150 64th of 123 higher than 60 of 123 other Smoking trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Smoking trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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