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NCT05571917 · ClinicalTrials.gov registry record · NA
Healing Opioid Misuse and Pain Through Engagement (HOPE) Trial
A NA study of Chronic Pain and Opioid Use Disorder, sponsored by University of New Mexi.
- Active
- Registry status
- NA
- Development phase
- 160
- Enrollment target
- 2
- Study locations
NCT05571917: Active NA study of Chronic Pain and Opioid Use Disorder, sponsored by University of New Mexi.
NCT05571917 is a NA study of Chronic Pain and Opioid Use Disorder that is active but no longer recruiting, run by University of New Mexi. The registered enrollment target is 160 participants, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (79% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05571917, a NA study of Chronic Pain and Opioid Use Disorder, is active but no longer recruiting, sponsored by University of New Mexi.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 160 participants
- Enrollment target
- 2
- Study locations
Study Summary
This study is a multisite randomized clinical trial of a treatment designed to reduce pain interference while simultaneously addressing relapse prevention among individuals who have co-occurring chronic pain and Opioid Use Disorder (OUD). This study will recruit approximately 160 individuals who are currently being treated in clinics specializing in the physician management of OUD. To increase generalizability of study findings and increase internal validity of the physician management component of treatment, all participants will be stabilized on buprenorphine for OUD as part of their usual clinical care. Individuals will be randomized to either: (1) enhanced usual care or (2) the integrated ACT + MBRP treatment. The investigators hypothesize that: (1) the combination of ACT + MBRP in buprenorphine-prescribed patients with chronic pain will be more efficacious across primary and secondary outcome measures in comparison to Enhanced Usual Care and (2) examination of treatment mechanism data will indicate treatment-related changes that are consistent with the theoretical models of ACT+MBRP.
Primary Outcome
Pain interference between participants randomized to ACT+MBRP vs EUC assessed by Pain interference will be measured via Patient Reported Outcome Measurement Information System (PROMIS) Bank v1.0 Pain Interference: The National Institutes of Health (NIH) PROMIS toolkit measure for pain interference. Each item ranges from 0 (not at all) to 5 (very much interfered) and higher scores reflect more severe pain interference. This questionnaire asks about pain interference in the past 7 days (collected
Conditions Studied
Interventions
- BEHAVIORAL Acceptance and Commitment Therapy + Mindfulness Based Relapse Prevention (ACT + MBRP)
- BEHAVIORAL Enhance Usual Care (EUC)
Study Locations (2)
Michigan
- University of Michigan - Ann Arbor
New Mexico
- University of New Mexico - Albuquerque
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 160 participants |
| Start Date | 2023-05-05 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What the registry record for NCT05571917 still lists
NCT05571917 is an interventional study that assigns participants to a tested intervention. The registered 160 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (79% lower).
The record links to 2 conditions, with Chronic Pain appearing as the primary indexed condition, and to 2 interventions - of which Acceptance and Commitment Therapy + Mindfulness Based Relapse Prevention (ACT + MBRP) is the first listed.
NCT05571917 reports a single indexed study location in Michigan, New Mexico.
Frequently Asked Questions
What is clinical trial NCT05571917 about?
NCT05571917 is a clinical study titled "Healing Opioid Misuse and Pain Through Engagement (HOPE) Trial". This study is a multisite randomized clinical trial of a treatment designed to reduce pain interference while simultaneously addressing relapse prevention among individuals who have co-occurring chronic pain and Opioid Use Disorder (OUD). This study will recruit approximately 160 individuals who are...
What is the current status of trial NCT05571917?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 160 participants. The study started on 2023-05-05. Estimated completion is 2026-12-31.
What conditions does trial NCT05571917 study?
This clinical trial studies the following conditions: Chronic Pain, Opioid Use Disorder.
What interventions are being tested in trial NCT05571917?
The interventions under investigation include: Acceptance and Commitment Therapy + Mindfulness Based Relapse Prevention (ACT + MBRP) (BEHAVIORAL), Enhance Usual Care (EUC) (BEHAVIORAL).
Who is sponsoring clinical trial NCT05571917?
This trial is sponsored by University of New Mexi, which has 76 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05571917 being conducted?
This trial has 2 study locations across Michigan, New Mexico. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05571917's enrollment target sits among peer trials
160 97th of 301 higher than 203 of 301 other Chronic Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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