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Linezolid for Syphilis Pilot Study
NCT05548426 · View on ClinicalTrials.gov ↗
Study Summary
The study aims to evaluate the efficacy of linezolid for the treatment of syphilis.
Conditions Studied
Interventions
- DRUG Group B, Linezolid 10d
- DRUG Group A, Penicillin
Study Locations (5)
Mississippi
- Open Arms HealthCare Center — Jackson
- University of Mississippi Medical Center — Jackson
Illinois
- Howard Brown Health — Chicago
North Carolina
- Wake Forest Baptist Health — Greensboro
Rhode Island
- Open Door Health — Providence
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2023-09-28 |
| Est. Completion | 2026-08 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05548426
The ClinicalTrials.gov registry entry for NCT05548426 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Southern California, which has 412 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Syphilis appearing as the primary indexed condition, and to 2 interventions — of which Group B, Linezolid 10d is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05548426 reports 5 study locations spanning 4 distinct geographic areas — top geographies include Mississippi, Illinois, North Carolina. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05548426 about?
NCT05548426 is a clinical study titled "Linezolid for Syphilis Pilot Study". The study aims to evaluate the efficacy of linezolid for the treatment of syphilis.
What is the current status of trial NCT05548426?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2023-09-28. Estimated completion is 2026-08.
What conditions does trial NCT05548426 study?
This clinical trial studies the following conditions: Syphilis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05548426?
The interventions under investigation include: Group B, Linezolid 10d (DRUG), Group A, Penicillin (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05548426?
This trial is sponsored by University of Southern California, which has 412 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05548426 being conducted?
This trial has 5 study locations across Illinois, Mississippi, North Carolina, Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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