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NCT05548426 · ClinicalTrials.gov registry record · Phase 2
Linezolid for Syphilis Pilot Study
A Phase 2 study of Syphilis, sponsored by University of Southern California.
- Active
- Registry status
- Phase 2
- Development phase
- 24
- Enrollment target
- 5
- Study locations
NCT05548426: Active Phase 2 study of Syphilis, sponsored by University of Southern California.
NCT05548426 is a Phase 2 study of Syphilis that is active but no longer recruiting, run by University of Southern California. The registered enrollment target is 24 participants, below the 270-participant average among 6 other Syphilis trials with a reported enrollment target (91% lower). The trial reports 5 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05548426, a Phase 2 study of Syphilis, is active but no longer recruiting, sponsored by University of Southern California.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 24 participants
- Enrollment target
- 5
- Study locations
Study Summary
The study aims to evaluate the efficacy of linezolid for the treatment of syphilis.
Primary Outcome
Percentage of linezolid participants with a 4-fold decrease or greater in the serum RPR titer by 180 days after treatment
Conditions Studied
Interventions
- DRUG Group B, Linezolid 10d
- DRUG Group A, Penicillin
Study Locations (5)
Mississippi
- Open Arms HealthCare Center - Jackson
- University of Mississippi Medical Center - Jackson
Illinois
- Howard Brown Health - Chicago
North Carolina
- Wake Forest Baptist Health - Greensboro
Rhode Island
- Open Door Health - Providence
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2023-09-28 |
| Est. Completion | 2026-08 |
| Phase | Phase 2 |
What the registry record for NCT05548426 still lists
NCT05548426 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 270-participant average among 6 other Syphilis trials with a reported enrollment target (91% lower).
The record links to 1 condition, with Syphilis appearing as the primary indexed condition, and to 2 interventions - of which Group B, Linezolid 10d is the first listed.
NCT05548426 lists 5 locations in 4 states (Mississippi, Illinois, North Carolina).
Frequently Asked Questions
What is clinical trial NCT05548426 about?
NCT05548426 is a clinical study titled "Linezolid for Syphilis Pilot Study". The study aims to evaluate the efficacy of linezolid for the treatment of syphilis.
What is the current status of trial NCT05548426?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2023-09-28. Estimated completion is 2026-08.
What conditions does trial NCT05548426 study?
This clinical trial studies the following conditions: Syphilis.
What interventions are being tested in trial NCT05548426?
The interventions under investigation include: Group B, Linezolid 10d (DRUG), Group A, Penicillin (DRUG).
Who is sponsoring clinical trial NCT05548426?
This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05548426 being conducted?
This trial has 5 study locations across Illinois, Mississippi, North Carolina, Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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