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ACTIVE NOT RECRUITING NA

The Maximizing Extubation Outcomes Through Educational and Organizational Research (METEOR) Trial

NCT05523479 · View on ClinicalTrials.gov ↗

Study Summary

The METEOR Trial will compare four implementation strategies-traditional online education, protocol-directed care, interprofessional education, and a combination of protocol-directed care and interprofessional education-to test the hypotheses that interprofessional education is superior to traditional online education as an implementation strategy in the intensive care unit (ICU) and the benefits of interprofessional education are increased when interprofessional education is paired with a clinical protocol. Additionally, the trial will also test the hypothesis that preventive post-extubation NIV for high-risk patients and preventive post-extubation HFNC for low-risk patients are both superior to current clinical practice (i.e., conventional post-extubation oxygen therapy).

Interventions

  • BEHAVIORAL Traditional online education
  • BEHAVIORAL Interprofessional education
  • BEHAVIORAL Clinical protocol
  • OTHER Risk-stratified preventive post-extubation noninvasive ventilation (NIV) or high-flow nasal cannula oxygen (HFNC)
  • OTHER Preventive post-extubation high-flow nasal cannula oxygen (HFNC)

Study Locations (15)

Pennsylvania

  • UPMC Carlisle — Carlisle
  • UPMC Hanover — Hanover
  • UPMC Harrisburg — Harrisburg
  • UPMC Community Osteopathic — Harrisburg
  • UPMC West Shore — Mechanicsburg
  • UPMC East — Monroeville
  • UPMC Jameson — New Castle
  • University of Pittsburgh — Pittsburgh
  • UPMC Magee-Womens Hospital — Pittsburgh
  • UPMC Presbyterian — Pittsburgh
  • UPMC St. Margaret — Pittsburgh
  • UPMC Mercy — Pittsburgh
  • UPMC Shadyside — Pittsburgh
  • UPMC Passavant — Pittsburgh
  • UPMC Memorial — York

Trial Details

FieldValue
Enrollment Target 13,018 participants
Start Date 2023-03-01
Est. Completion 2026-04
Phase NA

Sponsor

University of Pittsburgh

1,082 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05523479

The ClinicalTrials.gov registry entry for NCT05523479 describes a study currently listed as active not recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 13,018 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pittsburgh, which has 1,082 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Acute Respiratory Failure appearing as the primary indexed condition, and to 5 interventions — of which Traditional online education is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05523479 reports 15 study locations spanning 1 distinct geographic area — top geographies include Pennsylvania. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05523479 about?

NCT05523479 is a clinical study titled "The Maximizing Extubation Outcomes Through Educational and Organizational Research (METEOR) Trial". The METEOR Trial will compare four implementation strategies-traditional online education, protocol-directed care, interprofessional education, and a combination of protocol-directed care and interprofessional education-to test the hypotheses that interprofessional education is superior to tradition...

What is the current status of trial NCT05523479?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 13,018 participants. The study started on 2023-03-01. Estimated completion is 2026-04.

What conditions does trial NCT05523479 study?

This clinical trial studies the following conditions: Acute Respiratory Failure, Airway Extubation. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05523479?

The interventions under investigation include: Traditional online education (BEHAVIORAL), Interprofessional education (BEHAVIORAL), Clinical protocol (BEHAVIORAL), Risk-stratified preventive post-extubation noninvasive ventilation (NIV) or high-flow nasal cannula oxygen (HFNC) (OTHER), Preventive post-extubation high-flow nasal cannula oxygen (HFNC) (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05523479?

This trial is sponsored by University of Pittsburgh, which has 1,082 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05523479 being conducted?

This trial has 15 study locations across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial