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NCT05517525 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Brensocatib in Participants With Normal Hepatic Function and Participants With Hepatic Impairment
A Phase 1 study of Hepatic Impairment, sponsored by Insmed Incorporated.
- Completed
- Registry status
- Phase 1
- Development phase
- 30
- Enrollment target
- 3
- Study locations
NCT05517525 is a Phase 1 study of Hepatic Impairment that has completed, run by Insmed Incorporated. The registered enrollment target is 30 participants, below the 36-participant average among 48 other Hepatic Impairment trials with a reported enrollment target (17% lower). The trial reports 3 study locations across 3 states.
The verdict
NCT05517525, a Phase 1 study of Hepatic Impairment, has completed, sponsored by Insmed Incorporated.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 30 participants
- Enrollment target
- 3
- Study locations
Study Summary
The primary purpose of the study is to compare the PK of a single dose of brensocatib in participants with hepatic impairment to that in matched healthy control participants with normal hepatic function.
Conditions Studied
Interventions
- DRUG Brensocatib
Study Locations (3)
California
- USA002 - Rialto
Florida
- USA003 - Orlando
Texas
- USA001 - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2022-10-04 |
| Est. Completion | 2023-06-01 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05517525
The ClinicalTrials.gov registry entry for NCT05517525 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 36-participant average among 48 other Hepatic Impairment trials with a reported enrollment target (17% lower). The listed sponsor is Insmed Incorporated, which has 31 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Hepatic Impairment appearing as the primary indexed condition, and to 1 intervention - of which Brensocatib is the first listed.
NCT05517525 reports 3 study locations spanning 3 distinct geographic areas - top geographies include California, Florida, Texas.
Frequently Asked Questions
What is clinical trial NCT05517525 about?
NCT05517525 is a clinical study titled "A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Brensocatib in Participants With Normal Hepatic Function and Participants With Hepatic Impairment". The primary purpose of the study is to compare the PK of a single dose of brensocatib in participants with hepatic impairment to that in matched healthy control participants with normal hepatic function.
What is the current status of trial NCT05517525?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2022-10-04. Estimated completion is 2023-06-01.
What conditions does trial NCT05517525 study?
This clinical trial studies the following conditions: Hepatic Impairment.
What interventions are being tested in trial NCT05517525?
The interventions under investigation include: Brensocatib (DRUG).
Who is sponsoring clinical trial NCT05517525?
This trial is sponsored by Insmed Incorporated, which has 31 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05517525 being conducted?
This trial has 3 study locations across California, Florida, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.