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NCT05517525 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Brensocatib in Participants With Normal Hepatic Function and Participants With Hepatic Impairment
A Phase 1 study of Hepatic Impairment, sponsored by Insmed Incorporated.
- Completed
- Registry status
- Phase 1
- Development phase
- 30
- Enrollment target
- 3
- Study locations
NCT05517525: Completed Phase 1 study of Hepatic Impairment, sponsored by Insmed Incorporated.
NCT05517525 is a Phase 1 study of Hepatic Impairment that has completed, run by Insmed Incorporated. The registered enrollment target is 30 participants, below the 36-participant average among 48 other Hepatic Impairment trials with a reported enrollment target (17% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05517525, a Phase 1 study of Hepatic Impairment, has completed, sponsored by Insmed Incorporated.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 30 participants
- Enrollment target
- 3
- Study locations
Study Summary
The primary purpose of the study is to compare the PK of a single dose of brensocatib in participants with hepatic impairment to that in matched healthy control participants with normal hepatic function.
Primary Outcome
Comparison of the pharmacokinetics of a single dose of brensocatib in participants with hepatic impairment to that in matched healthy control participants with normal hepatic function.
Conditions Studied
Interventions
- DRUG Brensocatib
Study Locations (3)
California
- USA002 - Rialto
Florida
- USA003 - Orlando
Texas
- USA001 - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2022-10-04 |
| Est. Completion | 2023-06-01 |
| Phase | Phase 1 |
What the finished NCT05517525 record still lists
NCT05517525 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 36-participant average among 48 other Hepatic Impairment trials with a reported enrollment target (17% lower).
The record links to 1 condition, with Hepatic Impairment appearing as the primary indexed condition, and to 1 intervention - of which Brensocatib is the first listed.
NCT05517525 reports a single indexed study location in California, Florida, Texas.
Frequently Asked Questions
What is clinical trial NCT05517525 about?
NCT05517525 is a clinical study titled "A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Brensocatib in Participants With Normal Hepatic Function and Participants With Hepatic Impairment". The primary purpose of the study is to compare the PK of a single dose of brensocatib in participants with hepatic impairment to that in matched healthy control participants with normal hepatic function.
What is the current status of trial NCT05517525?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2022-10-04. Estimated completion is 2023-06-01.
What conditions does trial NCT05517525 study?
This clinical trial studies the following conditions: Hepatic Impairment.
What interventions are being tested in trial NCT05517525?
The interventions under investigation include: Brensocatib (DRUG).
Who is sponsoring clinical trial NCT05517525?
This trial is sponsored by Insmed Incorporated, which has 31 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05517525 being conducted?
This trial has 3 study locations across California, Florida, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hepatic Impairment
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05517525's enrollment target sits among peer trials
30 21st of 48 higher than 24 of 48 other Hepatic Impairment trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hepatic Impairment trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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