Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05461326 · ClinicalTrials.gov registry record · NA
Quadriceps Tendon Versus Bone Patellar Tendon Bone Autograft ACL Reconstruction RCT
A NA study of Anterior Cruciate Ligament Injuries and Orthopedic Disorder, sponsored by University of Alabama at Birmingham.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT05461326: Recruiting NA study of Anterior Cruciate Ligament Injuries and Orthopedic Disorder, sponsored by University of Alabama at Birmingham.
NCT05461326 is a NA study of Anterior Cruciate Ligament Injuries and Orthopedic Disorder that is actively recruiting participants, run by University of Alabama at Birmingham. The registered enrollment target is 100 participants, below the 319-participant average among 24 other Anterior Cruciate Ligament Injuries trials with a reported enrollment target (69% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05461326, a NA study of Anterior Cruciate Ligament Injuries and Orthopedic Disorder, is actively recruiting participants, sponsored by University of Alabama at Birmingham.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The choice of autograft for ACL reconstruction continues to be debated. To date, there has only be one completed randomized controlled trial with quad tendon to BTB and the tendon included a bone plug. There has been no study to date comparing an all soft tissue quad tendon to patellar tendon in a randomized controlled trial for ACL reconstruction.
Primary Outcome
Measures maximum side-to-side difference of laxity (translation of the tibia in comparison to a fix femur)
Conditions Studied
Interventions
- PROCEDURE Quad tendon
- PROCEDURE BTB
Study Locations (1)
Alabama
- UAB Hospital Highlands - Birmingham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2023-09-26 |
| Est. Completion | 2030-06-30 |
| Phase | NA |
What NCT05461326 shows while recruiting
NCT05461326 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 319-participant average among 24 other Anterior Cruciate Ligament Injuries trials with a reported enrollment target (69% lower).
The record links to 2 conditions, with Anterior Cruciate Ligament Injuries appearing as the primary indexed condition, and to 2 interventions - of which Quad tendon is the first listed.
NCT05461326 reports a single indexed study location in Alabama.
Frequently Asked Questions
What is clinical trial NCT05461326 about?
NCT05461326 is a clinical study titled "Quadriceps Tendon Versus Bone Patellar Tendon Bone Autograft ACL Reconstruction RCT". The choice of autograft for ACL reconstruction continues to be debated. To date, there has only be one completed randomized controlled trial with quad tendon to BTB and the tendon included a bone plug. There has been no study to date comparing an all soft tissue quad tendon to patellar tendon in a r...
What is the current status of trial NCT05461326?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2023-09-26. Estimated completion is 2030-06-30.
What conditions does trial NCT05461326 study?
This clinical trial studies the following conditions: Anterior Cruciate Ligament Injuries, Orthopedic Disorder.
What interventions are being tested in trial NCT05461326?
The interventions under investigation include: Quad tendon (PROCEDURE), BTB (PROCEDURE).
Who is sponsoring clinical trial NCT05461326?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05461326 being conducted?
This trial has 1 study location across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Anterior Cruciate Ligament Injuries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05461326's enrollment target sits among peer trials
100 10th of 24 higher than 15 of 24 other Anterior Cruciate Ligament Injuries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Anterior Cruciate Ligament Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Anterior Cruciate Ligament Recovery With Virtual Psychological Intervention
RECRUITING · NA
-
Steps Towards Osteoarthritis Prevention
RECRUITING · NA
-
Gait Rehabilitation to Treat FastOA
RECRUITING · NA
-
Dynamic Muscular Electrical Stimulation Following Anterior Cruciate Ligament Reconstruction in Military Academy Cadets
RECRUITING · NA
-
Bracing and Reconstruction of the Anterior Cruciate Ligament for Efficacy Trial
RECRUITING · NA
-
External Focus of Attention Feedback to Reduce Risk of Non-contact ACL Injury
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01048281 · 100 participants
Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma
- NCT01161199 · 100 participants
The Use of Leukapheresis to Support HIV Pathogenesis Studies
- NCT01327690 · 100 participants · Early Phase 1
Mental Health in Veterans and Families After Group Therapies
- NCT01730781 · 100 participants
Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI