Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06193343 · ClinicalTrials.gov registry record · NA
Steps Towards Osteoarthritis Prevention
A NA study of Anterior Cruciate Ligament Injuries, sponsored by University of Georgia.
- Recruiting
- Registry status
- NA
- Development phase
- 56
- Enrollment target
- 1
- Study location
NCT06193343: Recruiting NA study of Anterior Cruciate Ligament Injuries, sponsored by University of Georgia.
NCT06193343 is a NA study of Anterior Cruciate Ligament Injuries that is actively recruiting participants, run by University of Georgia. The registered enrollment target is 56 participants, below the 321-participant average among 24 other Anterior Cruciate Ligament Injuries trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06193343, a NA study of Anterior Cruciate Ligament Injuries, is actively recruiting participants, sponsored by University of Georgia.
- RECRUITING
- Registry status
- NA
- Development phase
- 56 participants
- Enrollment target
- 1
- Study location
Study Summary
Optimal knee joint loading, which refers to the forces acting on the knee caused by daily activities such as daily steps, plays an essential role in maintaining knee articular cartilage health and reducing the risk of osteoarthritis (OA). After anterior cruciate ligament reconstruction (ACLR), individuals take fewer daily steps as compared to uninjured controls resulting in insufficient knee joint loading to joint tissues, but it is unclear how changes in daily steps impact knee joint cartilage health in OA development. Therefore, the overall single arm, longitudinal pre-test post-test study objective is to determine the mechanistic links between knee joint loading as measured by daily steps and comprehensive magnetic resonance imaging (MRI) measures of knee joint cartilage health post-ACLR. The central hypothesis is that individuals post-ACLR who take low daily steps will demonstrate deconditioned, less resilient cartilage characterized by poor tibiofemoral cartilage composition and greater cartilage strain.
Primary Outcome
MRI marker of T2 relaxation times of medial femoral articular cartilage (i.e collagen organization) at pre-intervention (baseline)
Conditions Studied
Interventions
- BEHAVIORAL Adaptive Daily Step Promotion
Study Locations (1)
Georgia
- University of Georgia - Athens
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2024-09-23 |
| Est. Completion | 2028-01-30 |
| Phase | NA |
What NCT06193343 shows while recruiting
NCT06193343 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 56 participants, a relatively small participant target, below the 321-participant average among 24 other Anterior Cruciate Ligament Injuries trials with a reported enrollment target (83% lower).
The record links to 1 condition, with Anterior Cruciate Ligament Injuries appearing as the primary indexed condition, and to 1 intervention - of which Adaptive Daily Step Promotion is the first listed.
NCT06193343 reports a single indexed study location in Georgia.
Frequently Asked Questions
What is clinical trial NCT06193343 about?
NCT06193343 is a clinical study titled "Steps Towards Osteoarthritis Prevention". Optimal knee joint loading, which refers to the forces acting on the knee caused by daily activities such as daily steps, plays an essential role in maintaining knee articular cartilage health and reducing the risk of osteoarthritis (OA). After anterior cruciate ligament reconstruction (ACLR), indiv...
What is the current status of trial NCT06193343?
This trial is currently recruiting. It is a NA study. The enrollment target is 56 participants. The study started on 2024-09-23. Estimated completion is 2028-01-30.
What conditions does trial NCT06193343 study?
This clinical trial studies the following conditions: Anterior Cruciate Ligament Injuries.
What interventions are being tested in trial NCT06193343?
The interventions under investigation include: Adaptive Daily Step Promotion (BEHAVIORAL).
Who is sponsoring clinical trial NCT06193343?
This trial is sponsored by University of Georgia, which has 59 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06193343 being conducted?
This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Anterior Cruciate Ligament Injuries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06193343's enrollment target sits among peer trials
56 18th of 24 higher than 6 of 24 other Anterior Cruciate Ligament Injuries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Anterior Cruciate Ligament Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Anterior Cruciate Ligament Recovery With Virtual Psychological Intervention
RECRUITING · NA
-
Gait Rehabilitation to Treat FastOA
RECRUITING · NA
-
Dynamic Muscular Electrical Stimulation Following Anterior Cruciate Ligament Reconstruction in Military Academy Cadets
RECRUITING · NA
-
Quadriceps Tendon Versus Bone Patellar Tendon Bone Autograft ACL Reconstruction RCT
RECRUITING · NA
-
Bracing and Reconstruction of the Anterior Cruciate Ligament for Efficacy Trial
RECRUITING · NA
-
External Focus of Attention Feedback to Reduce Risk of Non-contact ACL Injury
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02287428 · 56 participants · Phase 1
Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM
- NCT02923011 · 56 participants · Phase 3
Comparative Effectiveness of MRgFUS Versus CTgRFA for Osteoid Osteomas
- NCT02935283 · 56 participants
Neuroimaging and Neuropsychological Outcomes in Urea Cycle Disorders
- NCT03375866 · 56 participants · NA
Effects of Mixed Nut Consumption on Satiety and Weight Management
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI