Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05457140 · ClinicalTrials.gov registry record · NA
Multiomic Diagnostics in Youth With Psychosis
A NA study of Psychosis, sponsored by Rady Pediatric Genomics & Systems Medicine Institute.
- Recruiting
- Registry status
- NA
- Development phase
- 15
- Enrollment target
- 1
- Study location
NCT05457140: Recruiting NA study of Psychosis, sponsored by Rady Pediatric Genomics & Systems Medicine Institute.
NCT05457140 is a NA study of Psychosis that is actively recruiting participants, run by Rady Pediatric Genomics & Systems Medicine Institute. The registered enrollment target is 15 participants, below the 178-participant average among 35 other Psychosis trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05457140, a NA study of Psychosis, is actively recruiting participants, sponsored by Rady Pediatric Genomics & Systems Medicine Institute.
- RECRUITING
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
- 1
- Study location
Study Summary
Rady Children's Institute for Genomic Medicine seeks to understand the genomes and immune systems in 15 children and adolescents who are admitted to Rady Children's Hospital Child and Adolescent Psychiatry Service with psychotic symptoms or schizophrenia. Cutting-edge genome and protein sequencing technology will be used to better understand how immunological and genetic assessments may improve our ability to identify the cause of psychosis and impact care. The investigator also hopes to identify new genetic and/or autoimmune causes of psychosis that may inform new treatment for future patients.
Primary Outcome
Diagnostic rate of brain reactive autoantibodies via genomic and whole human proteome programmable phage display immunoprecipitation sequencing (PhIP-Seq)
Conditions Studied
Interventions
- GENETIC Genetic: Genomic sequencing and molecular diagnostic results, if any.
- DIAGNOSTIC_TEST Phage display ImmunoPrecipiation Sequencing (PhIP-Seq)
Study Locations (1)
California
- Rady Children's Hospital San Diego - San Diego
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2022-10-10 |
| Est. Completion | 2026-08 |
| Phase | NA |
What NCT05457140 shows while recruiting
NCT05457140 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 178-participant average among 35 other Psychosis trials with a reported enrollment target (92% lower).
The record links to 1 condition, with Psychosis appearing as the primary indexed condition, and to 2 interventions - of which Genetic: Genomic sequencing and molecular diagnostic results, if any. is the first listed.
NCT05457140 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05457140 about?
NCT05457140 is a clinical study titled "Multiomic Diagnostics in Youth With Psychosis". Rady Children's Institute for Genomic Medicine seeks to understand the genomes and immune systems in 15 children and adolescents who are admitted to Rady Children's Hospital Child and Adolescent Psychiatry Service with psychotic symptoms or schizophrenia. Cutting-edge genome and protein sequencing t...
What is the current status of trial NCT05457140?
This trial is currently recruiting. It is a NA study. The enrollment target is 15 participants. The study started on 2022-10-10. Estimated completion is 2026-08.
What conditions does trial NCT05457140 study?
This clinical trial studies the following conditions: Psychosis.
What interventions are being tested in trial NCT05457140?
The interventions under investigation include: Genetic: Genomic sequencing and molecular diagnostic results, if any. (GENETIC), Phage display ImmunoPrecipiation Sequencing (PhIP-Seq) (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT05457140?
This trial is sponsored by Rady Pediatric Genomics & Systems Medicine Institute, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05457140 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Psychosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05457140's enrollment target sits among peer trials
15 35th of 35 higher than 1 of 35 other Psychosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Psychosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
A Mental Health Services Engagement Program for Racial and Ethnic Minority Young Adults
RECRUITING · NA
-
Determining the Role of Social Reward Learning in Social Anhedonia
RECRUITING · NA
-
Cerebellar Modulation of Cognition in Psychosis
RECRUITING · NA
-
Precision Brain Stimulation to Reduce Cannabis Craving in Schizophrenia
RECRUITING · NA
-
Acute Psychiatric Care at Home for Lower-risk Patients With Acute Psychiatric Illness Who Require Inpatient Care
RECRUITING · NA
-
Targeting Emotion Dysregulation to Reduce Suicide in People With Psychosis
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01889381 · 15 participants · Phase 2
Human Craniomaxillofacial Allotransplantation
- NCT02530073 · 15 participants · NA
Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) for CDH
- NCT02535936 · 15 participants · NA
Cortical Plasticity in Spastic Diplegia After Selective Dorsal Rhizotomy
- NCT02918474 · 15 participants · NA
Decision Making Tool in Supporting Decision Making in Contralateral Prophylactic Mastectomy in Patients With Newly Diagnosed Breast Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI