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NCT05442034 · ClinicalTrials.gov registry record · Phase 1
Rh-PDGF vs EMD for Treatment of Intra-bony Defects
A Phase 1 study of Intrabony Periodontal Defect, sponsored by Nova Southeastern University.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 36
- Enrollment target
- 1
- Study location
NCT05442034 is a Phase 1 study of Intrabony Periodontal Defect that is actively recruiting participants, run by Nova Southeastern University. The registered enrollment target is 36 participants. The trial reports 1 study location across 1 state.
The verdict
NCT05442034, a Phase 1 study of Intrabony Periodontal Defect, is actively recruiting participants, sponsored by Nova Southeastern University.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 36 participants
- Enrollment target
- 1
- Study location
Study Summary
Treatment of intra-bony defects is challenging and requires extensive knowledge of the etiology, anatomy, occlusion, and available biomaterials that can be used to treat this kind of defects. Patients who received scaling and root planing at the college of dental medicine due to periodontal disease, will be screened for inclusion. Only subjects who showed persistent deep probing depth associated with an intrabony defect will be included and will be randomly allocated to one of two treatment groups. One group will be treated using recombinant human platelet derived growth factor (GEM-21) (test) added to allogenic bone graft, second group will be treated using enamel matrix derivatives (EMD) (control) with allograft. Both groups will be treated using the same surgical protocol. Patients will be followed up for a period of 6 months, before getting re-evaluated for assessing the effectiveness of the applied therapies.
Conditions Studied
Interventions
- BIOLOGICAL growth factors to help in regeneration
Study Locations (1)
Florida
- Nova Southeastern University - Davie
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2023-01-01 |
| Est. Completion | 2025-06-30 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05442034
The ClinicalTrials.gov registry entry for NCT05442034 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Nova Southeastern University, which has 71 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Intrabony Periodontal Defect appearing as the primary indexed condition, and to 1 intervention - of which growth factors to help in regeneration is the first listed.
NCT05442034 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.
Frequently Asked Questions
What is clinical trial NCT05442034 about?
NCT05442034 is a clinical study titled "Rh-PDGF vs EMD for Treatment of Intra-bony Defects". Treatment of intra-bony defects is challenging and requires extensive knowledge of the etiology, anatomy, occlusion, and available biomaterials that can be used to treat this kind of defects. Patients who received scaling and root planing at the college of dental medicine due to periodontal disease,...
What is the current status of trial NCT05442034?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2023-01-01. Estimated completion is 2025-06-30.
What conditions does trial NCT05442034 study?
This clinical trial studies the following conditions: Intrabony Periodontal Defect.
What interventions are being tested in trial NCT05442034?
The interventions under investigation include: growth factors to help in regeneration (BIOLOGICAL).
Who is sponsoring clinical trial NCT05442034?
This trial is sponsored by Nova Southeastern University, which has 71 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05442034 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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