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NCT05433103 · ClinicalTrials.gov registry record · NA
Blood Flow Restriction And Veterans With MS
A NA study of Multiple Sclerosis, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 58
- Enrollment target
- 1
- Study location
NCT05433103: Recruiting NA study of Multiple Sclerosis, sponsored by VA Office of Research and Development.
NCT05433103 is a NA study of Multiple Sclerosis that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 58 participants, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05433103, a NA study of Multiple Sclerosis, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 58 participants
- Enrollment target
- 1
- Study location
Study Summary
There currently is a lack of evidence to support exercise interventions in people with advanced disability due to MS (i.e., need assistance to walk or use a wheelchair). This project proposes to study a strength training program using blood flow restriction (BFR) in people with advanced disability due to MS. BFR uses a device that partially blocks blood flow to the exercising limb and causes a response in the muscle which can replicate the effects of high-intensity training using much lower intensities. This is ideal for people with MS who have advanced disability, as they often cannot tolerate higher intensity exercise due to severe weakness and fatigue. By studying BFR training in people with advanced disability due to MS, the investigators hope to help improve strength, mobility, fatigue, and quality of life in people with MS. This study will target enrollment of Veterans with MS, who tend to have more advanced disability than non-Veterans with MS.
Primary Outcome
Quadriceps muscle strength measured using dynamometry.
Conditions Studied
Interventions
- OTHER Low-Load Exercise with Blood Flow Restriction
- OTHER Low-Load Exercise Control Group
Study Locations (1)
Colorado
- Rocky Mountain Regional VA Medical Center, Aurora, CO - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 58 participants |
| Start Date | 2023-01-01 |
| Est. Completion | 2027-12-31 |
| Phase | NA |
What NCT05433103 shows while recruiting
NCT05433103 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 58 participants, a relatively small participant target, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (90% lower).
The record links to 1 condition, with Multiple Sclerosis appearing as the primary indexed condition, and to 2 interventions - of which Low-Load Exercise with Blood Flow Restriction is the first listed.
NCT05433103 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT05433103 about?
NCT05433103 is a clinical study titled "Blood Flow Restriction And Veterans With MS". There currently is a lack of evidence to support exercise interventions in people with advanced disability due to MS (i.e., need assistance to walk or use a wheelchair). This project proposes to study a strength training program using blood flow restriction (BFR) in people with advanced disability d...
What is the current status of trial NCT05433103?
This trial is currently recruiting. It is a NA study. The enrollment target is 58 participants. The study started on 2023-01-01. Estimated completion is 2027-12-31.
What conditions does trial NCT05433103 study?
This clinical trial studies the following conditions: Multiple Sclerosis.
What interventions are being tested in trial NCT05433103?
The interventions under investigation include: Low-Load Exercise with Blood Flow Restriction (OTHER), Low-Load Exercise Control Group (OTHER).
Who is sponsoring clinical trial NCT05433103?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05433103 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Multiple Sclerosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05433103's enrollment target sits among peer trials
58 171st of 315 higher than 145 of 315 other Multiple Sclerosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Multiple Sclerosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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