Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05430009 · ClinicalTrials.gov registry record · Phase 1

Liver SBRT in Combination With Immune Checkpoint Inhibition in Patients With Metastatic Non-small Cell Lung Cancer

A Phase 1 study of Non-Small Cell Lung Cancer and Liver Metastases, sponsored by VA Ann Arbor Healthcare System.

Recruiting
Registry status
Phase 1
Development phase
12
Enrollment target
1
Study location

NCT05430009 is a Phase 1 study of Non-Small Cell Lung Cancer and Liver Metastases that is actively recruiting participants, run by VA Ann Arbor Healthcare System. The registered enrollment target is 12 participants, below the 659-participant average among 449 other Non-Small Cell Lung Cancer trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05430009, a Phase 1 study of Non-Small Cell Lung Cancer and Liver Metastases, is actively recruiting participants, sponsored by VA Ann Arbor Healthcare System.

RECRUITING
Registry status
Phase 1
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

Determine the feasibility of liver stereotactic body radiation therapy (SBRT) given in combination with systemic therapy (immune checkpoint inhibitors) in adult patients with metastatic NSCLC with liver metastases.

Interventions

  • DRUG Pembrolizumab
  • RADIATION Liver SBRT

Study Locations (1)

Michigan

  • Veterans Affairs Ann Arbor Healthcare System - Ann Arbor

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2022-06-17
Est. Completion 2026-06-15
Phase Phase 1

Sponsor

VA Ann Arbor Healthcare System

5 total trials

What the Registry Record Tells You About NCT05430009

The ClinicalTrials.gov registry entry for NCT05430009 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 659-participant average among 449 other Non-Small Cell Lung Cancer trials with a reported enrollment target (98% lower). The listed sponsor is VA Ann Arbor Healthcare System, which has 5 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Non-Small Cell Lung Cancer appearing as the primary indexed condition, and to 2 interventions - of which Pembrolizumab is the first listed.

NCT05430009 reports 1 study location spanning 1 distinct geographic area - top geographies include Michigan.

Frequently Asked Questions

What is clinical trial NCT05430009 about?

NCT05430009 is a clinical study titled "Liver SBRT in Combination With Immune Checkpoint Inhibition in Patients With Metastatic Non-small Cell Lung Cancer". Determine the feasibility of liver stereotactic body radiation therapy (SBRT) given in combination with systemic therapy (immune checkpoint inhibitors) in adult patients with metastatic NSCLC with liver metastases.

What is the current status of trial NCT05430009?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2022-06-17. Estimated completion is 2026-06-15.

What conditions does trial NCT05430009 study?

This clinical trial studies the following conditions: Non-Small Cell Lung Cancer, Liver Metastases.

What interventions are being tested in trial NCT05430009?

The interventions under investigation include: Pembrolizumab (DRUG), Liver SBRT (RADIATION).

Who is sponsoring clinical trial NCT05430009?

This trial is sponsored by VA Ann Arbor Healthcare System, which has 5 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05430009 being conducted?

This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Non-Small Cell Lung Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.