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NCT05423691 · ClinicalTrials.gov registry record · Phase 1

Leading in MPNs Beyond Ruxolitinib in Combo With T-Regs

A Phase 1 study of Myelofibrosis, sponsored by Cellenkos.

Recruiting
Registry status
Phase 1
Development phase
24
Enrollment target
4
Study locations

NCT05423691 is a Phase 1 study of Myelofibrosis that is actively recruiting participants, run by Cellenkos. The registered enrollment target is 24 participants, below the 195-participant average among 61 other Myelofibrosis trials with a reported enrollment target (88% lower). The trial reports 4 study locations across 3 states.

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The verdict

NCT05423691, a Phase 1 study of Myelofibrosis, is actively recruiting participants, sponsored by Cellenkos.

RECRUITING
Registry status
Phase 1
Development phase
24 participants
Enrollment target
4
Study locations

Study Summary

To assess the safety and tolerability of CK0804 as add-on therapy in participants with myelofibrosis, with suboptimal response to ruxolitinib

Conditions Studied

Interventions

  • DRUG CK0804

Study Locations (4)

New York

  • Columbia University - New York
  • Montefiore Einstein Cancer Center - The Bronx

California

  • UC Davis Health - Sacramento

Texas

  • The University of Texas MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2022-12-27
Est. Completion 2026-12-30
Phase Phase 1

Sponsor

Cellenkos

4 total trials

What the Registry Record Tells You About NCT05423691

The ClinicalTrials.gov registry entry for NCT05423691 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 195-participant average among 61 other Myelofibrosis trials with a reported enrollment target (88% lower). The listed sponsor is Cellenkos, which has 4 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Myelofibrosis appearing as the primary indexed condition, and to 1 intervention - of which CK0804 is the first listed.

NCT05423691 reports 4 study locations spanning 3 distinct geographic areas - top geographies include New York, California, Texas.

Frequently Asked Questions

What is clinical trial NCT05423691 about?

NCT05423691 is a clinical study titled "Leading in MPNs Beyond Ruxolitinib in Combo With T-Regs". To assess the safety and tolerability of CK0804 as add-on therapy in participants with myelofibrosis, with suboptimal response to ruxolitinib

What is the current status of trial NCT05423691?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2022-12-27. Estimated completion is 2026-12-30.

What conditions does trial NCT05423691 study?

This clinical trial studies the following conditions: Myelofibrosis.

What interventions are being tested in trial NCT05423691?

The interventions under investigation include: CK0804 (DRUG).

Who is sponsoring clinical trial NCT05423691?

This trial is sponsored by Cellenkos, which has 4 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05423691 being conducted?

This trial has 4 study locations across California, New York, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.