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NCT05412381 · ClinicalTrials.gov registry record · Phase 3

PRP in ACLR to Prevent PTOA

A Phase 3 study of Anterior Cruciate Ligament Injuries and Post-traumatic Osteoarthritis, sponsored by Hospital for Special Surgery, New York.

Recruiting
Registry status
Phase 3
Development phase
56
Enrollment target
1
Study location

NCT05412381 is a Phase 3 study of Anterior Cruciate Ligament Injuries and Post-traumatic Osteoarthritis that is actively recruiting participants, run by Hospital for Special Surgery, New York. The registered enrollment target is 56 participants, below the 321-participant average among 24 other Anterior Cruciate Ligament Injuries trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05412381, a Phase 3 study of Anterior Cruciate Ligament Injuries and Post-traumatic Osteoarthritis, is actively recruiting participants, sponsored by Hospital for Special Surgery, New York.

RECRUITING
Registry status
Phase 3
Development phase
56 participants
Enrollment target
1
Study location

Study Summary

The purpose of our study is to examine the effect of platelet-rich-plasma (PRP) injection on the short-term resolution of post-injury inflammation (biomarkers) and improvement in joint function in patients with acute ACL injury. This RCT has been powered based on the questionnaire KOOS Jr. but it is considered a 'pilot study' in terms of the lab analysis proposed.

Conditions Studied

Anterior Cruciate Ligament Injuries Post-traumatic Osteoarthritis PRP

Interventions

  • PROCEDURE platelet rich plasma (PRP) injection
  • PROCEDURE placebo saline injection

Study Locations (1)

New York

  • Hospital for Special Surgery - New York

Trial Details

FieldValue
Enrollment Target 56 participants
Start Date 2022-06-27
Est. Completion 2026-12-31
Phase Phase 3

Sponsor

Hospital for Special Surgery, New York

194 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05412381

The ClinicalTrials.gov registry entry for NCT05412381 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 56 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 321-participant average among 24 other Anterior Cruciate Ligament Injuries trials with a reported enrollment target (83% lower). The listed sponsor is Hospital for Special Surgery, New York, which has 194 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Anterior Cruciate Ligament Injuries appearing as the primary indexed condition, and to 2 interventions - of which platelet rich plasma (PRP) injection is the first listed.

NCT05412381 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT05412381 about?

NCT05412381 is a clinical study titled "PRP in ACLR to Prevent PTOA". The purpose of our study is to examine the effect of platelet-rich-plasma (PRP) injection on the short-term resolution of post-injury inflammation (biomarkers) and improvement in joint function in patients with acute ACL injury. This RCT has been powered based on the questionnaire KOOS Jr. but it is...

What is the current status of trial NCT05412381?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 56 participants. The study started on 2022-06-27. Estimated completion is 2026-12-31.

What conditions does trial NCT05412381 study?

This clinical trial studies the following conditions: Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, PRP.

What interventions are being tested in trial NCT05412381?

The interventions under investigation include: platelet rich plasma (PRP) injection (PROCEDURE), placebo saline injection (PROCEDURE).

Who is sponsoring clinical trial NCT05412381?

This trial is sponsored by Hospital for Special Surgery, New York, which has 194 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05412381 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.