Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05391828 · ClinicalTrials.gov registry record · NA
Persona MC vs PS RCT With ROSA
A NA study of Total Knee Arthroplasty, sponsored by NYU Langone Health.
- Recruiting
- Registry status
- NA
- Development phase
- 200
- Enrollment target
- 1
- Study location
NCT05391828: Recruiting NA study of Total Knee Arthroplasty, sponsored by NYU Langone Health.
NCT05391828 is a NA study of Total Knee Arthroplasty that is actively recruiting participants, run by NYU Langone Health. The registered enrollment target is 200 participants, below the 288-participant average among 29 other Total Knee Arthroplasty trials with a reported enrollment target (31% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05391828, a NA study of Total Knee Arthroplasty, is actively recruiting participants, sponsored by NYU Langone Health.
- RECRUITING
- Registry status
- NA
- Development phase
- 200 participants
- Enrollment target
- 1
- Study location
Study Summary
A randomized, controlled study comparing two total knee implant devices, Persona medial congruent (MC) vs posterior stabilized (PS). These surgeries will be performed using the ROSA robotic system. Patients will be followed up to 5 years.
Primary Outcome
KOOS, JR contains 7 items from the original KOOS survey. Items are coded from 0 to 4, none to extreme respectively. KOOS, JR is scored by summing the raw response (range 0-28) and then converting it to an interval score. The interval score ranges from 0 to 100 where 0 represents total knee disability and 100 represents perfect knee health.
Conditions Studied
Interventions
- DEVICE Zimmer-Biomet Persona Medial Congruent (MC) Bearing Design
- DEVICE Zimmer-Biomet Persona Posterior-Stabilized (PS) Bearing Design
Study Locations (1)
New York
- NYU Langone Health - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2023-09-27 |
| Est. Completion | 2026-12 |
| Phase | NA |
What NCT05391828 shows while recruiting
NCT05391828 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 288-participant average among 29 other Total Knee Arthroplasty trials with a reported enrollment target (31% lower).
The record links to 1 condition, with Total Knee Arthroplasty appearing as the primary indexed condition, and to 2 interventions - of which Zimmer-Biomet Persona Medial Congruent (MC) Bearing Design is the first listed.
NCT05391828 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT05391828 about?
NCT05391828 is a clinical study titled "Persona MC vs PS RCT With ROSA". A randomized, controlled study comparing two total knee implant devices, Persona medial congruent (MC) vs posterior stabilized (PS). These surgeries will be performed using the ROSA robotic system. Patients will be followed up to 5 years.
What is the current status of trial NCT05391828?
This trial is currently recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2023-09-27. Estimated completion is 2026-12.
What conditions does trial NCT05391828 study?
This clinical trial studies the following conditions: Total Knee Arthroplasty.
What interventions are being tested in trial NCT05391828?
The interventions under investigation include: Zimmer-Biomet Persona Medial Congruent (MC) Bearing Design (DEVICE), Zimmer-Biomet Persona Posterior-Stabilized (PS) Bearing Design (DEVICE).
Who is sponsoring clinical trial NCT05391828?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05391828 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Total Knee Arthroplasty
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05391828's enrollment target sits among peer trials
200 6th of 29 higher than 22 of 29 other Total Knee Arthroplasty trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Total Knee Arthroplasty trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Intraoperative VR for Older Patients Undergoing TKA
RECRUITING · NA
-
Investigating Patient Satisfaction With Smart Knee Implants
RECRUITING · NA
-
Enhanced Recovery After Major Surgery and Chronic Pain for Total Knee Arthroplasty
RECRUITING · NA
-
Minimal Sedation During Knee Replacement Surgery
RECRUITING · NA
-
Effectiveness of Exparel Anesthetic Administered by the Surgeon During Knee Surgery
RECRUITING · NA
-
Implementation of Neuromuscular Electrical Stimulation After Total Knee Arthroplasty
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00107289 · 200 participants · Phase 2
Iodine I 131 Metaiodobenzylguanidine in Treating Patients With Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or Paraganglioma
- NCT00109174 · 200 participants · NA
MRS Measurement of Glutamate and GABA Metabolism in Brain
- NCT00177268 · 200 participants
Blood, Urine, and Tissue Collection for Cutaneous Lymphoma, Eczema, and Atopic Dermatitis Research
- NCT00493688 · 200 participants
A Study to Determine Whether Perioperative Energy Dynamics Correlates With Postoperative Outcomes
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI