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NCT05387811 · ClinicalTrials.gov registry record
International Registry of Acute Kidney Injury in Cirrhosis: The GLOBAL AKI Project
A clinical trial of Acute Kidney Injury and Liver Cirrhosis, sponsored by Azienda Ospedaliera di Padova.
- Completed
- Registry status
- 1,456
- Enrollment target
- 20
- Study locations
NCT05387811: Completed study of Acute Kidney Injury and Liver Cirrhosis, sponsored by Azienda Ospedaliera di Padova.
NCT05387811 is a study of Acute Kidney Injury and Liver Cirrhosis that has completed, run by Azienda Ospedaliera di Padova. The registered enrollment target is 1,456 participants, below the 2,311-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (37% lower). The trial reports 20 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05387811, a study of Acute Kidney Injury and Liver Cirrhosis, has completed, sponsored by Azienda Ospedaliera di Padova.
- COMPLETED
- Registry status
- 1,456 participants
- Enrollment target
- 20
- Study locations
Study Summary
The aims of this study will be to identify the clinical characteristics, the management and the outcomes of acute kidney injury in patients with cirrhosis worldwide. Specific aims: 1. To establish the severity of AKI across different regions 2. To identify precipitants of AKI across different centers 3. To identify the phenotypes of AKI across different centers 4. To evaluate differences in the management of AKI across different centers and their impact on clinical outcomes 5. To assess outcomes of acute kidney injury (resolution of AKI, in-hospital mortality, 28-day mortality, 90-day mortality)
Primary Outcome
Mortality at 90 days
Conditions Studied
Interventions
- COMBINATION_PRODUCT Crystalloids, albumin, vasoconstrictors, diuretics, renal replacement therapy
Study Locations (20)
Other
- Hospital de Gastroenterología "Dr. Carlos Bonorino Udaondo" - Buenos Aires
- Hospital Italiano - Buenos Aires
- Hospital Nacional Prof. Alejandro Posadas - El Palomar
- Universidad de Rosario - Rosario
- Hospital Federal de Bonsoccesso - Rio de Janeiro
- Universidad de Chile - Santiago
- Shanghai Jiao Tong University School of Medicine - Shanghai
- Hvidovre Hospital - Copenhagen
- Ain Shams University - Cairo
- Black Lion Hospital - Addis Ababa
- Jean Minjoz University Hospital - Besançon
- Hospital Beaujon - Clichy
- University of Aachen - Aachen
- University Hospital Munich - Munich
- Hospital of Debrecen - Debrecen
Indiana
- Indiana University - Indianapolis
Louisiana
- Ochsner Medical Center - New Orleans
Massachusetts
- Massachusetts General Hospital - Boston
Texas
- Baylor University Medical Center - Dallas
Virginia
- University of Virginia - Charlottesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,456 participants |
| Start Date | 2022-07-01 |
| Est. Completion | 2023-11-30 |
What the finished NCT05387811 record still lists
NCT05387811 is an observational study that tracks outcomes without assigning an intervention. Its 1,456 participants enrollment target places it among the larger protocols in the corpus, below the 2,311-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (37% lower).
The record links to 3 conditions, with Acute Kidney Injury appearing as the primary indexed condition, and to 1 intervention - of which Crystalloids, albumin, vasoconstrictors, diuretics, renal replacement therapy is the first listed.
NCT05387811 names 20 study sites across 6 states, led by Other, Indiana, Louisiana.
Frequently Asked Questions
What is clinical trial NCT05387811 about?
NCT05387811 is a clinical study titled "International Registry of Acute Kidney Injury in Cirrhosis: The GLOBAL AKI Project". The aims of this study will be to identify the clinical characteristics, the management and the outcomes of acute kidney injury in patients with cirrhosis worldwide. Specific aims: 1. To establish the severity of AKI across different regions 2. To identify precipitants of AKI across different cent...
What is the current status of trial NCT05387811?
This trial is currently completed. The enrollment target is 1,456 participants. The study started on 2022-07-01. Estimated completion is 2023-11-30.
What conditions does trial NCT05387811 study?
This clinical trial studies the following conditions: Acute Kidney Injury, Liver Cirrhosis, Hepatorenal Syndrome.
What interventions are being tested in trial NCT05387811?
The interventions under investigation include: Crystalloids, albumin, vasoconstrictors, diuretics, renal replacement therapy (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT05387811?
This trial is sponsored by Azienda Ospedaliera di Padova, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05387811 being conducted?
This trial has 20 study locations across Indiana, Louisiana, Massachusetts, Texas, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Where NCT05387811's enrollment target sits among peer trials
1,456 10th of 74 higher than 65 of 74 other Acute Kidney Injury trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Kidney Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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