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NCT05374317 · ClinicalTrials.gov registry record · Phase 4
Study of the Safety and Immunogenicity of Reduced Doses of the US Yellow Fever Vaccine
A Phase 4 study of Yellow Fever Vaccination Reaction, sponsored by US Army Medical Research Institute of Infectious Diseases.
- Completed
- Registry status
- Phase 4
- Development phase
- 88
- Enrollment target
- 1
- Study location
NCT05374317 is a Phase 4 study of Yellow Fever Vaccination Reaction that has completed, run by US Army Medical Research Institute of Infectious Diseases. The registered enrollment target is 88 participants. The trial reports 1 study location across 1 state.
The verdict
NCT05374317, a Phase 4 study of Yellow Fever Vaccination Reaction, has completed, sponsored by US Army Medical Research Institute of Infectious Diseases.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 88 participants
- Enrollment target
- 1
- Study location
Study Summary
This is an open-label, randomized, exploratory study to evaluate the human immune response to reduced subcutaneous (SQ) dosing of Yellow Fever vaccine compared to the standard FDA approved subcutaneous vaccination dose. The current dose of the US FDA licensed Yellow Fever vaccine is approximately 55,000 plaque-forming unit(s) (PFU) in 0.5 mL administered SQ. Using the licensed dosage as standard, investigators are evaluating reduced doses of 1/5th (0.10 mL) and 1/10th (0.05 mL) Yellow Fever vaccine (YF-VAX).
Conditions Studied
Interventions
- BIOLOGICAL Yellow Fever Vaccine
Study Locations (1)
Maryland
- United States Army Medical Research Institute of Infectious Diseases - Frederick
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 88 participants |
| Start Date | 2021-06-07 |
| Est. Completion | 2022-11-02 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05374317
The ClinicalTrials.gov registry entry for NCT05374317 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 88 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is US Army Medical Research Institute of Infectious Diseases, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Yellow Fever Vaccination Reaction appearing as the primary indexed condition, and to 1 intervention - of which Yellow Fever Vaccine is the first listed.
NCT05374317 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT05374317 about?
NCT05374317 is a clinical study titled "Study of the Safety and Immunogenicity of Reduced Doses of the US Yellow Fever Vaccine". This is an open-label, randomized, exploratory study to evaluate the human immune response to reduced subcutaneous (SQ) dosing of Yellow Fever vaccine compared to the standard FDA approved subcutaneous vaccination dose. The current dose of the US FDA licensed Yellow Fever vaccine is approximately 55...
What is the current status of trial NCT05374317?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 88 participants. The study started on 2021-06-07. Estimated completion is 2022-11-02.
What conditions does trial NCT05374317 study?
This clinical trial studies the following conditions: Yellow Fever Vaccination Reaction.
What interventions are being tested in trial NCT05374317?
The interventions under investigation include: Yellow Fever Vaccine (BIOLOGICAL).
Who is sponsoring clinical trial NCT05374317?
This trial is sponsored by US Army Medical Research Institute of Infectious Diseases, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05374317 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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