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Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis
NCT05369234 · View on ClinicalTrials.gov ↗
Study Summary
As mentioned above, several prior studies have shown the positive effects of oral use of aloe vera juice in managing chemotherapy and radiation-induced oral mucositis and esophagitis. This study aims to add to the existing body of research around aloe vera juice and its effects on oral mucositis and esophagitis. The intention is to determine whether aloe vera juice should be considered as part of standard treatment.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT 100% Aloe Vera Juice
- COMBINATION_PRODUCT Magic Mouthwash
- COMBINATION_PRODUCT Salt and Baking soda rinse
- DRUG Carafate
Study Locations (1)
Tennessee
- Thompson Cancer Survival Center Radiation Oncology Services — Knoxville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2022-01-20 |
| Est. Completion | 2024-01-30 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05369234
The ClinicalTrials.gov registry entry for NCT05369234 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Covenant Health Cancer Center, which has 4 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 8 conditions, with Esophageal Cancer appearing as the primary indexed condition, and to 4 interventions — of which 100% Aloe Vera Juice is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05369234 reports 1 study location spanning 1 distinct geographic area — top geographies include Tennessee. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05369234 about?
NCT05369234 is a clinical study titled "Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis". As mentioned above, several prior studies have shown the positive effects of oral use of aloe vera juice in managing chemotherapy and radiation-induced oral mucositis and esophagitis. This study aims to add to the existing body of research around aloe vera juice and its effects on oral mucositis and...
What is the current status of trial NCT05369234?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 100 participants. The study started on 2022-01-20. Estimated completion is 2024-01-30.
What conditions does trial NCT05369234 study?
This clinical trial studies the following conditions: Esophageal Cancer, Oropharynx Cancer, Oral Cavity Cancer, Laryngeal Cancer, Head and Neck Cancers - Tonsils. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05369234?
The interventions under investigation include: 100% Aloe Vera Juice (DIETARY_SUPPLEMENT), Magic Mouthwash (COMBINATION_PRODUCT), Salt and Baking soda rinse (COMBINATION_PRODUCT), Carafate (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05369234?
This trial is sponsored by Covenant Health Cancer Center, which has 4 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05369234 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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