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NCT05369234 · ClinicalTrials.gov registry record · Phase 3
Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis
A Phase 3 study of Esophageal Cancer and Oropharynx Cancer, sponsored by Covenant Health Cancer Center.
- Completed
- Registry status
- Phase 3
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT05369234: Completed Phase 3 study of Esophageal Cancer and Oropharynx Cancer, sponsored by Covenant Health Cancer Center.
NCT05369234 is a Phase 3 study of Esophageal Cancer and Oropharynx Cancer that has completed, run by Covenant Health Cancer Center. The registered enrollment target is 100 participants, below the 498-participant average among 123 other Esophageal Cancer trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05369234, a Phase 3 study of Esophageal Cancer and Oropharynx Cancer, has completed, sponsored by Covenant Health Cancer Center.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
As mentioned above, several prior studies have shown the positive effects of oral use of aloe vera juice in managing chemotherapy and radiation-induced oral mucositis and esophagitis. This study aims to add to the existing body of research around aloe vera juice and its effects on oral mucositis and esophagitis. The intention is to determine whether aloe vera juice should be considered as part of standard treatment.
Primary Outcome
to determine whether to add oral aloe vera juice to standard of care treatments for lip, oral cavity, hard palate, tongue, tonsil , pharyngeal, laryngeal, neck , esophageal, mediastinal, and chest wall cancers will help prevent oral mucositis and esophagitis symptoms while patients undergo radiation therapy. Symptoms will be assessed using the CTCAE v. 5.0 weekly while on treatment to determine if the addition of aloe vera juice impacts these symptoms when compared to subjects that don't receive
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT 100% Aloe Vera Juice
- COMBINATION_PRODUCT Magic Mouthwash
- COMBINATION_PRODUCT Salt and Baking soda rinse
- DRUG Carafate
Study Locations (1)
Tennessee
- Thompson Cancer Survival Center Radiation Oncology Services - Knoxville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2022-01-20 |
| Est. Completion | 2024-01-30 |
| Phase | Phase 3 |
What the finished NCT05369234 record still lists
NCT05369234 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 498-participant average among 123 other Esophageal Cancer trials with a reported enrollment target (80% lower).
The record links to 8 conditions, with Esophageal Cancer appearing as the primary indexed condition, and to 4 interventions - of which 100% Aloe Vera Juice is the first listed.
NCT05369234 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT05369234 about?
NCT05369234 is a clinical study titled "Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis". As mentioned above, several prior studies have shown the positive effects of oral use of aloe vera juice in managing chemotherapy and radiation-induced oral mucositis and esophagitis. This study aims to add to the existing body of research around aloe vera juice and its effects on oral mucositis and...
What is the current status of trial NCT05369234?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 100 participants. The study started on 2022-01-20. Estimated completion is 2024-01-30.
What conditions does trial NCT05369234 study?
This clinical trial studies the following conditions: Esophageal Cancer, Oropharynx Cancer, Oral Cavity Cancer, Laryngeal Cancer, Head and Neck Cancers - Tonsils.
What interventions are being tested in trial NCT05369234?
The interventions under investigation include: 100% Aloe Vera Juice (DIETARY_SUPPLEMENT), Magic Mouthwash (COMBINATION_PRODUCT), Salt and Baking soda rinse (COMBINATION_PRODUCT), Carafate (DRUG).
Who is sponsoring clinical trial NCT05369234?
This trial is sponsored by Covenant Health Cancer Center, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05369234 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05369234's enrollment target sits among peer trials
100 51st of 123 higher than 69 of 123 other Esophageal Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Esophageal Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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