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NCT05368350 · ClinicalTrials.gov registry record · NA
Treating Primary Progressive Aphasia and Apraxia of Speech Using Non-invasive Brain Stimulation
A NA study of Primary Progressive Aphasia and Apraxia of Speech, sponsored by The University of Texas at Dallas.
- Active
- Registry status
- NA
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT05368350: Active NA study of Primary Progressive Aphasia and Apraxia of Speech, sponsored by The University of Texas at Dallas.
NCT05368350 is a NA study of Primary Progressive Aphasia and Apraxia of Speech that is active but no longer recruiting, run by The University of Texas at Dallas. The registered enrollment target is 12 participants, below the 92-participant average among 15 other Primary Progressive Aphasia trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05368350, a NA study of Primary Progressive Aphasia and Apraxia of Speech, is active but no longer recruiting, sponsored by The University of Texas at Dallas.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the study is to test whether low level electric stimulation, called transcranial Direct Current Stimulation (tDCS), on the part of the brain (i.e., pre-supplementary motor area and left inferior frontal gyrus) thought to aid in memory will improve speech and language difficulties in patients with primary progressive aphasia (PPA) and progressive apraxia of speech (PAOS). The primary outcome measures are neuropsychological assessments of speech and language functions, and the secondary measures are neuropsychological assessments of other cognitive abilities and electroencephalography (EEG) measures.
Primary Outcome
Evaluation of treatment differences in change on the Control Word Association Test Benton, L.A., Hamsher, K., \& Sivan, A.B., (1994). Multilingual aphasia examination. Iowa City: AJA Associates.
Conditions Studied
Interventions
- DEVICE high-definition transcranial direct current stimulation (HD-tDCS)
Study Locations (1)
Texas
- The University of Texas at Dallas - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2022-06-01 |
| Est. Completion | 2026-04-16 |
| Phase | NA |
What the registry record for NCT05368350 still lists
NCT05368350 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 92-participant average among 15 other Primary Progressive Aphasia trials with a reported enrollment target (87% lower).
The record links to 2 conditions, with Primary Progressive Aphasia appearing as the primary indexed condition, and to 1 intervention - of which high-definition transcranial direct current stimulation (HD-tDCS) is the first listed.
NCT05368350 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT05368350 about?
NCT05368350 is a clinical study titled "Treating Primary Progressive Aphasia and Apraxia of Speech Using Non-invasive Brain Stimulation". The purpose of the study is to test whether low level electric stimulation, called transcranial Direct Current Stimulation (tDCS), on the part of the brain (i.e., pre-supplementary motor area and left inferior frontal gyrus) thought to aid in memory will improve speech and language difficulties in p...
What is the current status of trial NCT05368350?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 12 participants. The study started on 2022-06-01. Estimated completion is 2026-04-16.
What conditions does trial NCT05368350 study?
This clinical trial studies the following conditions: Primary Progressive Aphasia, Apraxia of Speech.
What interventions are being tested in trial NCT05368350?
The interventions under investigation include: high-definition transcranial direct current stimulation (HD-tDCS) (DEVICE).
Who is sponsoring clinical trial NCT05368350?
This trial is sponsored by The University of Texas at Dallas, which has 50 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05368350 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Primary Progressive Aphasia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05368350's enrollment target sits among peer trials
12 13th of 15 higher than 2 of 15 other Primary Progressive Aphasia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Primary Progressive Aphasia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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Enhancing Language Function in Aphasia
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-
Enhancing Language Function in Primary Progressive Aphasia
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-
Targeting Language-specific and Executive-control Networks With Transcranial Direct Current Stimulation in Logopenic Variant PPA
RECRUITING · NA
-
Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia
RECRUITING · NA
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Treatment for Speech and Language in Primary Progressive Aphasia
ACTIVE NOT RECRUITING · NA
-
Communication Bridge Pilot Study
ACTIVE NOT RECRUITING · NA
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