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NCT05366738 · ClinicalTrials.gov registry record · Phase 1

A Study to Determine the Bioavailability of Vonoprazan Sprinkle Capsules on Pudding or on Applesauce Relative to a Vonoprazan Tablet in Healthy Participants

A Phase 1 study of Healthy Volunteers, sponsored by Phathom Pharmaceuticals.

Completed
Registry status
Phase 1
Development phase
27
Enrollment target
1
Study location

NCT05366738: Completed Phase 1 study of Healthy Volunteers, sponsored by Phathom Pharmaceuticals.

NCT05366738 is a Phase 1 study of Healthy Volunteers that has completed, run by Phathom Pharmaceuticals. The registered enrollment target is 27 participants, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05366738, a Phase 1 study of Healthy Volunteers, has completed, sponsored by Phathom Pharmaceuticals.

COMPLETED
Registry status
Phase 1
Development phase
27 participants
Enrollment target
1
Study location

Study Summary

The primary objective of this study is to assess the bioavailability (BA) of a single oral dose of vonoprazan 20 mg sprinkle capsule, either sprinkled on pudding or on applesauce, relative to a vonoprazan 20 mg tablet in healthy participants.

Conditions Studied

Interventions

  • DRUG Vonoprazan

Study Locations (1)

Texas

  • PPD Development, LP - Austin

Trial Details

FieldValue
Enrollment Target 27 participants
Start Date 2022-05-18
Est. Completion 2022-07-26
Phase Phase 1
Phathom Pharmaceuticals

13 total trials

What the finished NCT05366738 record still lists

NCT05366738 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (94% lower).

The record links to 1 condition, with Healthy Volunteers appearing as the primary indexed condition, and to 1 intervention - of which Vonoprazan is the first listed.

NCT05366738 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT05366738 about?

NCT05366738 is a clinical study titled "A Study to Determine the Bioavailability of Vonoprazan Sprinkle Capsules on Pudding or on Applesauce Relative to a Vonoprazan Tablet in Healthy Participants". The primary objective of this study is to assess the bioavailability (BA) of a single oral dose of vonoprazan 20 mg sprinkle capsule, either sprinkled on pudding or on applesauce, relative to a vonoprazan 20 mg tablet in healthy participants.

What is the current status of trial NCT05366738?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 27 participants. The study started on 2022-05-18. Estimated completion is 2022-07-26.

What conditions does trial NCT05366738 study?

This clinical trial studies the following conditions: Healthy Volunteers.

What interventions are being tested in trial NCT05366738?

The interventions under investigation include: Vonoprazan (DRUG).

Who is sponsoring clinical trial NCT05366738?

This trial is sponsored by Phathom Pharmaceuticals, which has 13 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05366738 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy Volunteers

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05366738's enrollment target sits among peer trials

27 200th of 283 higher than 84 of 283 other Healthy Volunteers trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Healthy Volunteers trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05366738, the US trial registry maintained by the National Library of Medicine. NCT05366738 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.