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NCT05365893 · ClinicalTrials.gov registry record · Early Phase 1

PHL Treatment in Pancreatic Cancer

A Early Phase 1 study of Pancreatic Ductal Adenocarcinoma, sponsored by Fox Chase Cancer Center.

Recruiting
Registry status
Early Phase 1
Development phase
20
Enrollment target
1
Study location

NCT05365893 is a Early Phase 1 study of Pancreatic Ductal Adenocarcinoma that is actively recruiting participants, run by Fox Chase Cancer Center. The registered enrollment target is 20 participants, below the 600-participant average among 84 other Pancreatic Ductal Adenocarcinoma trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05365893, a Early Phase 1 study of Pancreatic Ductal Adenocarcinoma, is actively recruiting participants, sponsored by Fox Chase Cancer Center.

RECRUITING
Registry status
Early Phase 1
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

This proposal will investigate the effect of paricalcitol, hydroxychloroquine, and losartan (PHL) combination of 3 stroma-modifying drugs on pancreatic adenocarcinoma and its stroma.

Interventions

  • COMBINATION_PRODUCT Paricalcitol, Hydroxychloroquine, Losartan
  • OTHER Neoadjuvant therapy and surgery only (Control)

Study Locations (1)

Pennsylvania

  • Fox Chase Cancer Center - Philadelphia

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2021-10-20
Est. Completion 2026-12-31
Phase Early Phase 1

Sponsor

Fox Chase Cancer Center

183 total trials

What the Registry Record Tells You About NCT05365893

The ClinicalTrials.gov registry entry for NCT05365893 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 600-participant average among 84 other Pancreatic Ductal Adenocarcinoma trials with a reported enrollment target (97% lower). The listed sponsor is Fox Chase Cancer Center, which has 183 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pancreatic Ductal Adenocarcinoma appearing as the primary indexed condition, and to 2 interventions - of which Paricalcitol, Hydroxychloroquine, Losartan is the first listed.

NCT05365893 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT05365893 about?

NCT05365893 is a clinical study titled "PHL Treatment in Pancreatic Cancer". This proposal will investigate the effect of paricalcitol, hydroxychloroquine, and losartan (PHL) combination of 3 stroma-modifying drugs on pancreatic adenocarcinoma and its stroma.

What is the current status of trial NCT05365893?

This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 20 participants. The study started on 2021-10-20. Estimated completion is 2026-12-31.

What conditions does trial NCT05365893 study?

This clinical trial studies the following conditions: Pancreatic Ductal Adenocarcinoma.

What interventions are being tested in trial NCT05365893?

The interventions under investigation include: Paricalcitol, Hydroxychloroquine, Losartan (COMBINATION_PRODUCT), Neoadjuvant therapy and surgery only (Control) (OTHER).

Who is sponsoring clinical trial NCT05365893?

This trial is sponsored by Fox Chase Cancer Center, which has 183 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05365893 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

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