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NCT05325970 · ClinicalTrials.gov registry record
Clinical Registry of Long-Term Dental Outcomes in Head and Neck Cancer Patients
A clinical trial of Head and Neck Cancer and Dental Diseases, sponsored by Wake Forest University Health Sciences.
- Active
- Registry status
- 350
- Enrollment target
- 6
- Study locations
NCT05325970: Active study of Head and Neck Cancer and Dental Diseases, sponsored by Wake Forest University Health Sciences.
NCT05325970 is a study of Head and Neck Cancer and Dental Diseases that is active but no longer recruiting, run by Wake Forest University Health Sciences. The registered enrollment target is 350 participants, above the 259-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (35% higher). The trial reports 6 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05325970, a study of Head and Neck Cancer and Dental Diseases, is active but no longer recruiting, sponsored by Wake Forest University Health Sciences.
- ACTIVE NOT RECRUITING
- Registry status
- 350 participants
- Enrollment target
- 6
- Study locations
Study Summary
The current study (ORARAD II) will examine participants of the original cohort for a visit roughly 7 years after the start of RT. The primary outcomes will be the 7-year rate of dental caries, periodontal disease, tooth loss, osteoradionecrosis and salivary flow.
Primary Outcome
Dental caries will be ascertained through the examination parameters outlined by NHANES, and the results of this examination with be used to calculate DMFS scores.
Conditions Studied
Study Locations (6)
Connecticut
- University of Connecticut Health Center - School of Dental Medicine - Farmington
Massachusetts
- Brigham and Women's Hospital - Boston
Minnesota
- University of Minnesota - Minneapolis
New York
- New York University - College of Dentistry - New York
North Carolina
- University of North Carolina School of Dentistry - Chapel Hill
Pennsylvania
- University of Pennsylvania School of Dental Medicine - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 350 participants |
| Start Date | 2014-02 |
| Est. Completion | 2026-06 |
What the registry record for NCT05325970 still lists
NCT05325970 is an observational study that tracks outcomes without assigning an intervention. The registered 350 participants enrollment target is mid-sized for trials with a published cap, above the 259-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (35% higher).
The record links to 3 conditions, with Head and Neck Cancer appearing as the primary indexed condition, and to 0 interventions.
NCT05325970 lists 6 locations in 6 states (Connecticut, Massachusetts, Minnesota).
Frequently Asked Questions
What is clinical trial NCT05325970 about?
NCT05325970 is a clinical study titled "Clinical Registry of Long-Term Dental Outcomes in Head and Neck Cancer Patients". The current study (ORARAD II) will examine participants of the original cohort for a visit roughly 7 years after the start of RT. The primary outcomes will be the 7-year rate of dental caries, periodontal disease, tooth loss, osteoradionecrosis and salivary flow.
What is the current status of trial NCT05325970?
This trial is currently active not recruiting. The enrollment target is 350 participants. The study started on 2014-02. Estimated completion is 2026-06.
What conditions does trial NCT05325970 study?
This clinical trial studies the following conditions: Head and Neck Cancer, Dental Diseases, Osteoradionecrosis.
Who is sponsoring clinical trial NCT05325970?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05325970 being conducted?
This trial has 6 study locations across Connecticut, Massachusetts, Minnesota, New York, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Head and Neck Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05325970's enrollment target sits among peer trials
350 29th of 250 higher than 222 of 250 other Head and Neck Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Head and Neck Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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