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ACTIVE NOT RECRUITING

Clinical Registry of Long-Term Dental Outcomes in Head and Neck Cancer Patients

NCT05325970 · View on ClinicalTrials.gov ↗

Study Summary

The current study (ORARAD II) will examine participants of the original cohort for a visit roughly 7 years after the start of RT. The primary outcomes will be the 7-year rate of dental caries, periodontal disease, tooth loss, osteoradionecrosis and salivary flow.

Study Locations (6)

Connecticut

  • University of Connecticut Health Center - School of Dental Medicine — Farmington

Massachusetts

  • Brigham and Women's Hospital — Boston

Minnesota

  • University of Minnesota — Minneapolis

New York

  • New York University - College of Dentistry — New York

North Carolina

  • University of North Carolina School of Dentistry — Chapel Hill

Pennsylvania

  • University of Pennsylvania School of Dental Medicine — Philadelphia

Trial Details

FieldValue
Enrollment Target 350 participants
Start Date 2014-02
Est. Completion 2026-06

Sponsor

Wake Forest University Health Sciences

1,061 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05325970

The ClinicalTrials.gov registry entry for NCT05325970 describes a study currently listed as active not recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 350 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Wake Forest University Health Sciences, which has 1,061 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Head and Neck Cancer appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05325970 reports 6 study locations spanning 6 distinct geographic areas — top geographies include Connecticut, Massachusetts, Minnesota. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05325970 about?

NCT05325970 is a clinical study titled "Clinical Registry of Long-Term Dental Outcomes in Head and Neck Cancer Patients". The current study (ORARAD II) will examine participants of the original cohort for a visit roughly 7 years after the start of RT. The primary outcomes will be the 7-year rate of dental caries, periodontal disease, tooth loss, osteoradionecrosis and salivary flow.

What is the current status of trial NCT05325970?

This trial is currently active not recruiting. The enrollment target is 350 participants. The study started on 2014-02. Estimated completion is 2026-06.

What conditions does trial NCT05325970 study?

This clinical trial studies the following conditions: Head and Neck Cancer, Dental Diseases, Osteoradionecrosis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

Who is sponsoring clinical trial NCT05325970?

This trial is sponsored by Wake Forest University Health Sciences, which has 1,061 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05325970 being conducted?

This trial has 6 study locations across Connecticut, Massachusetts, Minnesota, New York, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial