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NCT05303415 · ClinicalTrials.gov registry record · NA
Study of Low-intensity Focused Ultrasound Effects on Heat Evoked fMRI Signals
A NA study of Pain, sponsored by Virginia Polytechnic Institute and State University.
- Recruiting
- Registry status
- NA
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT05303415: Recruiting NA study of Pain, sponsored by Virginia Polytechnic Institute and State University.
NCT05303415 is a NA study of Pain that is actively recruiting participants, run by Virginia Polytechnic Institute and State University. The registered enrollment target is 80 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05303415, a NA study of Pain, is actively recruiting participants, sponsored by Virginia Polytechnic Institute and State University.
- RECRUITING
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
Study aims to examine the effects of noninvasive brain stimulation on brain signals. This insight may have potential clinical implications for addiction, pain, and mental health populations. Participants will receive MRI and CT imaging. Participants receive low-intensity focused ultrasound (LIFU) to temporarily change brain activity. Participants then receive fMRI scans to measure changes in both resting and heat evoked brain signaling using a quantitative sensory testing device. Heart rate, blood pressure, respiratory rate, and skin moisture is monitored. Participants complete a battery of questionnaires, both behavioral and symptom monitoring. The study takes place over 4 study visits.
Primary Outcome
Changes in fMRI BOLD signal
Conditions Studied
Interventions
- OTHER Neuromodulation with low-intensity focused ultrasound
Study Locations (1)
Virginia
- Fralin Biomedical Research Institute - Roanoke
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2022-05-06 |
| Est. Completion | 2027-12 |
| Phase | NA |
What NCT05303415 shows while recruiting
NCT05303415 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 304-participant average among 374 other Pain trials with a reported enrollment target (74% lower).
The record links to 1 condition, with Pain appearing as the primary indexed condition, and to 1 intervention - of which Neuromodulation with low-intensity focused ultrasound is the first listed.
NCT05303415 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT05303415 about?
NCT05303415 is a clinical study titled "Study of Low-intensity Focused Ultrasound Effects on Heat Evoked fMRI Signals". Study aims to examine the effects of noninvasive brain stimulation on brain signals. This insight may have potential clinical implications for addiction, pain, and mental health populations. Participants will receive MRI and CT imaging. Participants receive low-intensity focused ultrasound (LIFU) to...
What is the current status of trial NCT05303415?
This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2022-05-06. Estimated completion is 2027-12.
What conditions does trial NCT05303415 study?
This clinical trial studies the following conditions: Pain.
What interventions are being tested in trial NCT05303415?
The interventions under investigation include: Neuromodulation with low-intensity focused ultrasound (OTHER).
Who is sponsoring clinical trial NCT05303415?
This trial is sponsored by Virginia Polytechnic Institute and State University, which has 104 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05303415 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05303415's enrollment target sits among peer trials
80 193rd of 374 higher than 171 of 374 other Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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