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NCT05158335 · ClinicalTrials.gov registry record · Phase 1

Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of MBX 2109 in Healthy Adult Subjects

A Phase 1 study of Healthy, sponsored by MBX Biosciences.

Completed
Registry status
Phase 1
Development phase
76
Enrollment target
2
Study locations

NCT05158335 is a Phase 1 study of Healthy that has completed, run by MBX Biosciences. The registered enrollment target is 76 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (88% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT05158335, a Phase 1 study of Healthy, has completed, sponsored by MBX Biosciences.

COMPLETED
Registry status
Phase 1
Development phase
76 participants
Enrollment target
2
Study locations

Study Summary

The purpose of this trial is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple doses of MBX 2109 in healthy volunteers. This study includes 2 parts. Part A involves a single dose of MBX 2109 taken as a subcutaneous (SC) injection just under the skin. Part B involves repeat doses of MBX 2109 taken as a SC injection just under the skin. Each participant will enroll in only one part.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG MBX 2109 (Part A)
  • DRUG MBX 2109 (Part B)

Study Locations (2)

Texas

  • Labcorp Drug Development: Clinical Research Unit - Dallas

Wisconsin

  • Labcorp Drug Development: Clinical Research Unit - Madison

Trial Details

FieldValue
Enrollment Target 76 participants
Start Date 2021-11-10
Est. Completion 2023-06-20
Phase Phase 1

Sponsor

MBX Biosciences

7 total trials

What the Registry Record Tells You About NCT05158335

The ClinicalTrials.gov registry entry for NCT05158335 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 76 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (88% lower). The listed sponsor is MBX Biosciences, which has 7 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT05158335 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Texas, Wisconsin.

Frequently Asked Questions

What is clinical trial NCT05158335 about?

NCT05158335 is a clinical study titled "Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of MBX 2109 in Healthy Adult Subjects". The purpose of this trial is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple doses of MBX 2109 in healthy volunteers. This study includes 2 parts. Part A involves a single dose of MBX 2109 taken as a subcutaneous (SC) injection just under the skin...

What is the current status of trial NCT05158335?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 76 participants. The study started on 2021-11-10. Estimated completion is 2023-06-20.

What conditions does trial NCT05158335 study?

This clinical trial studies the following conditions: Healthy.

What interventions are being tested in trial NCT05158335?

The interventions under investigation include: Placebo (DRUG), MBX 2109 (Part A) (DRUG), MBX 2109 (Part B) (DRUG).

Who is sponsoring clinical trial NCT05158335?

This trial is sponsored by MBX Biosciences, which has 7 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05158335 being conducted?

This trial has 2 study locations across Texas, Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.