Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING NA

REMASTer: REcurrent Brain Metastases After SRS Trial

NCT05124912 · View on ClinicalTrials.gov ↗

Study Summary

Randomized, post-market multi-center study investigating the efficacy of two sets of treatment algorithms in brain metastases (BM) patients at the time of first intervention for radiographic progression after stereotactic radiosurgery (SRS), with or without surgery.

Interventions

  • DRUG Steroid Therapy
  • PROCEDURE Radiation Therapy
  • PROCEDURE Laser Interstitial Thermal Therapy

Study Locations (9)

North Carolina

  • Duke University Hospital — Durham
  • Wake Forest Baptist Medical Center — Winston-Salem

Ohio

  • Cleveland Clinic — Cleveland
  • Kettering Health — Kettering

California

  • UCLA — Los Angeles

Illinois

  • University of Chicago — Chicago

Maryland

  • University of Maryland — Baltimore

Missouri

  • WashU — St Louis

Wisconsin

  • Medical College of Wisconsin — Milwaukee

Trial Details

FieldValue
Enrollment Target 261 participants
Start Date 2022-05-10
Est. Completion 2028-10
Phase NA

Sponsor

Monteris Medical

3 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05124912

The ClinicalTrials.gov registry entry for NCT05124912 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 261 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Monteris Medical, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 4 conditions, with Brain Metastases appearing as the primary indexed condition, and to 3 interventions — of which Steroid Therapy is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05124912 reports 9 study locations spanning 7 distinct geographic areas — top geographies include North Carolina, Ohio, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05124912 about?

NCT05124912 is a clinical study titled "REMASTer: REcurrent Brain Metastases After SRS Trial". Randomized, post-market multi-center study investigating the efficacy of two sets of treatment algorithms in brain metastases (BM) patients at the time of first intervention for radiographic progression after stereotactic radiosurgery (SRS), with or without surgery.

What is the current status of trial NCT05124912?

This trial is currently recruiting. It is a NA study. The enrollment target is 261 participants. The study started on 2022-05-10. Estimated completion is 2028-10.

What conditions does trial NCT05124912 study?

This clinical trial studies the following conditions: Brain Metastases, Radiation Necrosis, Recurrent Tumor, Recurrent Metastases. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05124912?

The interventions under investigation include: Steroid Therapy (DRUG), Radiation Therapy (PROCEDURE), Laser Interstitial Thermal Therapy (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05124912?

This trial is sponsored by Monteris Medical, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05124912 being conducted?

This trial has 9 study locations across California, Illinois, Maryland, Missouri, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial