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NCT05124912 · ClinicalTrials.gov registry record · NA
REMASTer: REcurrent Brain Metastases After SRS Trial
A NA study of Brain Metastases and Radiation Necrosis, sponsored by Monteris Medical.
- Recruiting
- Registry status
- NA
- Development phase
- 261
- Enrollment target
- 9
- Study locations
NCT05124912: Recruiting NA study of Brain Metastases and Radiation Necrosis, sponsored by Monteris Medical.
NCT05124912 is a NA study of Brain Metastases and Radiation Necrosis that is actively recruiting participants, run by Monteris Medical. The registered enrollment target is 261 participants, above the 209-participant average among 67 other Brain Metastases trials with a reported enrollment target (25% higher). The trial reports 9 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05124912, a NA study of Brain Metastases and Radiation Necrosis, is actively recruiting participants, sponsored by Monteris Medical.
- RECRUITING
- Registry status
- NA
- Development phase
- 261 participants
- Enrollment target
- 9
- Study locations
Study Summary
Randomized, post-market multi-center study investigating the efficacy of two sets of treatment algorithms in brain metastases (BM) patients at the time of first intervention for radiographic progression after stereotactic radiosurgery (SRS), with or without surgery.
Primary Outcome
Determine the effectiveness of LITT using the NeuroBlate® System with or without repeat SRS on recurrent brain metastases, as measured by freedom from local progression.
Conditions Studied
Interventions
- DRUG Steroid Therapy
- PROCEDURE Radiation Therapy
- PROCEDURE Laser Interstitial Thermal Therapy
Study Locations (9)
North Carolina
- Duke University Hospital - Durham
- Wake Forest Baptist Medical Center - Winston-Salem
Ohio
- Cleveland Clinic - Cleveland
- Kettering Health - Kettering
California
- UCLA - Los Angeles
Illinois
- University of Chicago - Chicago
Maryland
- University of Maryland - Baltimore
Missouri
- WashU - St Louis
Wisconsin
- Medical College of Wisconsin - Milwaukee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 261 participants |
| Start Date | 2022-05-10 |
| Est. Completion | 2028-10 |
| Phase | NA |
What NCT05124912 shows while recruiting
NCT05124912 is an interventional study that assigns participants to a tested intervention. The registered 261 participants enrollment target is mid-sized for trials with a published cap, above the 209-participant average among 67 other Brain Metastases trials with a reported enrollment target (25% higher).
The record links to 4 conditions, with Brain Metastases appearing as the primary indexed condition, and to 3 interventions - of which Steroid Therapy is the first listed.
NCT05124912 lists 9 locations in 7 states (North Carolina, Ohio, California).
Frequently Asked Questions
What is clinical trial NCT05124912 about?
NCT05124912 is a clinical study titled "REMASTer: REcurrent Brain Metastases After SRS Trial". Randomized, post-market multi-center study investigating the efficacy of two sets of treatment algorithms in brain metastases (BM) patients at the time of first intervention for radiographic progression after stereotactic radiosurgery (SRS), with or without surgery.
What is the current status of trial NCT05124912?
This trial is currently recruiting. It is a NA study. The enrollment target is 261 participants. The study started on 2022-05-10. Estimated completion is 2028-10.
What conditions does trial NCT05124912 study?
This clinical trial studies the following conditions: Brain Metastases, Radiation Necrosis, Recurrent Tumor, Recurrent Metastases.
What interventions are being tested in trial NCT05124912?
The interventions under investigation include: Steroid Therapy (DRUG), Radiation Therapy (PROCEDURE), Laser Interstitial Thermal Therapy (PROCEDURE).
Who is sponsoring clinical trial NCT05124912?
This trial is sponsored by Monteris Medical, which has 8 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05124912 being conducted?
This trial has 9 study locations across California, Illinois, Maryland, Missouri, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Brain Metastases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05124912's enrollment target sits among peer trials
261 3rd of 67 higher than 65 of 67 other Brain Metastases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Brain Metastases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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