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NCT06074380 · ClinicalTrials.gov registry record · Phase 4
Non Inferiority Trial Investigating Surfactants Administered Via MIST
A Phase 4 study of Respiratory Distress Syndrome, sponsored by Endeavor Health.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 262
- Enrollment target
- 1
- Study location
NCT06074380: Recruiting Phase 4 study of Respiratory Distress Syndrome, sponsored by Endeavor Health.
NCT06074380 is a Phase 4 study of Respiratory Distress Syndrome that is actively recruiting participants, run by Endeavor Health. The registered enrollment target is 262 participants, above the 202-participant average among 8 other Respiratory Distress Syndrome trials with a reported enrollment target (30% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06074380, a Phase 4 study of Respiratory Distress Syndrome, is actively recruiting participants, sponsored by Endeavor Health.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 262 participants
- Enrollment target
- 1
- Study location
Study Summary
RESEARCH DESIGN Multicenter, randomized, controlled trial. RECRUITMENT Entry criteria Preterm infants 28-35 6/7 weeks' gestation and less than 48 hours of age who have a clinical diagnosis of respiratory distress syndrome. Infants who are on NCPAP and FiO2 ≥0.30 will randomized to curosurf or infasurf via MIST. Exclusion criteria Infants will be excluded if there is a congenital anomaly or an alternative cause for respiratory distress. Babies who require emergent intubation will not be enrolled in the interventions. Parental Consent will be obtained prior to randomization.
Primary Outcome
Infants will have an endotracheal placed if their inspired oxygen is \>45% for more than 15 minutes
Conditions Studied
Interventions
- DRUG MIST surfactant
Study Locations (1)
Illinois
- Northshore University Healthsystem - Evanston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 262 participants |
| Start Date | 2024-01-01 |
| Est. Completion | 2027-12-01 |
| Phase | Phase 4 |
What NCT06074380 shows while recruiting
NCT06074380 is an interventional study that assigns participants to a tested intervention. The registered 262 participants enrollment target is mid-sized for trials with a published cap, above the 202-participant average among 8 other Respiratory Distress Syndrome trials with a reported enrollment target (30% higher).
The record links to 1 condition, with Respiratory Distress Syndrome appearing as the primary indexed condition, and to 1 intervention - of which MIST surfactant is the first listed.
NCT06074380 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT06074380 about?
NCT06074380 is a clinical study titled "Non Inferiority Trial Investigating Surfactants Administered Via MIST". RESEARCH DESIGN Multicenter, randomized, controlled trial. RECRUITMENT Entry criteria Preterm infants 28-35 6/7 weeks' gestation and less than 48 hours of age who have a clinical diagnosis of respiratory distress syndrome. Infants who are on NCPAP and FiO2 ≥0.30 will randomized to curosurf or infasu...
What is the current status of trial NCT06074380?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 262 participants. The study started on 2024-01-01. Estimated completion is 2027-12-01.
What conditions does trial NCT06074380 study?
This clinical trial studies the following conditions: Respiratory Distress Syndrome.
What interventions are being tested in trial NCT06074380?
The interventions under investigation include: MIST surfactant (DRUG).
Who is sponsoring clinical trial NCT06074380?
This trial is sponsored by Endeavor Health, which has 94 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06074380 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Respiratory Distress Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06074380's enrollment target sits among peer trials
262 3rd of 8 higher than 6 of 8 other Respiratory Distress Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Respiratory Distress Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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