Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05089851 · ClinicalTrials.gov registry record · NA

Investigation of the Efficacy and Tolerability of a Cosmetic Product With Onabotulinumtoxin A in the Treatment of Facial Lines

A NA study, sponsored by Revision Skincare.

Completed
Registry status
NA
Development phase
29
Enrollment target

NCT05089851: Completed NA study, sponsored by Revision Skincare.

NCT05089851 is a NA study that has completed, run by Revision Skincare. The registered enrollment target is 29 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05089851, a NA study, has completed, sponsored by Revision Skincare.

COMPLETED
Registry status
NA
Development phase
29 participants
Enrollment target

Study Summary

This randomized, multi-center, double-blinded, placebo-controlled, split-face clinical trial was conducted to evaluate the procedure-pairing of OnabotulinumtoxinA with a peptide anti-aging serum to improve facial lines and wrinkles, as well as overall skin texture and radiance of the face after 12 weeks of twice-daily use in female subjects ages 35 - 60 as compared to placebo. A total of 29 subjects completed study participation.

Primary Outcome

The primary efficacy endpoint will be the Investigator Clinical Grading using Modified Griffith's 10 point scale. A change in scores at Day 28, Day 56, and Day 84 (+/- 3 days) in comparison to baseline indicates an improvement for the indicated parameter. The efficacy parameters will be assessed at rest and at maximum smile and at specific areas on both the left and right sides of the subjects face using a modified Griffith's 10 point scale according to the following numerical definitions (half

Interventions

  • COMBINATION_PRODUCT Sunscreen
  • PROCEDURE Onabotulinumtoxin A
  • COMBINATION_PRODUCT Facial Cleanser
  • COMBINATION_PRODUCT Facial Moisturizer

Trial Details

FieldValue
Enrollment Target 29 participants
Start Date 2020-08-23
Est. Completion 2021-06-03
Phase NA
Revision Skincare

18 total trials

What the finished NCT05089851 record still lists

NCT05089851 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 4 interventions - of which Sunscreen is the first listed.

NCT05089851 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05089851 about?

NCT05089851 is a clinical study titled "Investigation of the Efficacy and Tolerability of a Cosmetic Product With Onabotulinumtoxin A in the Treatment of Facial Lines". This randomized, multi-center, double-blinded, placebo-controlled, split-face clinical trial was conducted to evaluate the procedure-pairing of OnabotulinumtoxinA with a peptide anti-aging serum to improve facial lines and wrinkles, as well as overall skin texture and radiance of the face after 12 w...

What is the current status of trial NCT05089851?

This trial is currently completed. It is a NA study. The enrollment target is 29 participants. The study started on 2020-08-23. Estimated completion is 2021-06-03.

What interventions are being tested in trial NCT05089851?

The interventions under investigation include: Sunscreen (COMBINATION_PRODUCT), Onabotulinumtoxin A (PROCEDURE), Facial Cleanser (COMBINATION_PRODUCT), Facial Moisturizer (COMBINATION_PRODUCT).

Who is sponsoring clinical trial NCT05089851?

This trial is sponsored by Revision Skincare, which has 18 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05089851's enrollment target sits among peer trials

29 1702nd of 2000 higher than 297 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02429557 · 29 participants · Phase 1

    Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure

  • NCT02568878 · 29 participants · Phase 3

    Creatine for Depressed Male and Female Methamphetamine Users

  • NCT03014401 · 29 participants · NA

    The Effect of Adipose-Derived Stem Cells for Knee Osteoarthritis

  • NCT03128996 · 29 participants · Phase 1

    Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT05089851, the US trial registry maintained by the National Library of Medicine. NCT05089851 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.