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NCT05030298 · ClinicalTrials.gov registry record · Phase 1

Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial

A Phase 1 study of Malignant Glioma, sponsored by Mayo Clinic.

Recruiting
Registry status
Phase 1
Development phase
28
Enrollment target
2
Study locations

NCT05030298 is a Phase 1 study of Malignant Glioma that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 28 participants, below the 91-participant average among 40 other Malignant Glioma trials with a reported enrollment target (69% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT05030298, a Phase 1 study of Malignant Glioma, is actively recruiting participants, sponsored by Mayo Clinic.

RECRUITING
Registry status
Phase 1
Development phase
28 participants
Enrollment target
2
Study locations

Study Summary

This phase I trial finds out the possible benefits and/or side effects of radiosurgery before surgery (preoperative) in treating patients with high grade glioma. Radiosurgery uses special equipment to position the patient and precisely give a single large dose of radiation to the tumor. This method may kill tumor cells with fewer doses over a shorter period and cause less damage to normal tissue. Giving pre-operative radiosurgery may improve the odds of brain tumor control and reduce treatment-related side effects.

Conditions Studied

Interventions

  • RADIATION Radiation Therapy
  • DRUG Temozolomide
  • RADIATION Radiosurgery
  • PROCEDURE Stereotactic Biopsy
  • PROCEDURE Tumor Treating Fields Therapy

Study Locations (2)

Arizona

  • Mayo Clinic in Arizona - Phoenix

Florida

  • Mayo Clinic in Florida - Jacksonville

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2023-05-23
Est. Completion 2027-09-15
Phase Phase 1

Sponsor

Mayo Clinic

2,844 total trials

What the Registry Record Tells You About NCT05030298

The ClinicalTrials.gov registry entry for NCT05030298 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 28 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 91-participant average among 40 other Malignant Glioma trials with a reported enrollment target (69% lower). The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Malignant Glioma appearing as the primary indexed condition, and to 5 interventions - of which Radiation Therapy is the first listed.

NCT05030298 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Arizona, Florida.

Frequently Asked Questions

What is clinical trial NCT05030298 about?

NCT05030298 is a clinical study titled "Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial". This phase I trial finds out the possible benefits and/or side effects of radiosurgery before surgery (preoperative) in treating patients with high grade glioma. Radiosurgery uses special equipment to position the patient and precisely give a single large dose of radiation to the tumor. This method ...

What is the current status of trial NCT05030298?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 28 participants. The study started on 2023-05-23. Estimated completion is 2027-09-15.

What conditions does trial NCT05030298 study?

This clinical trial studies the following conditions: Malignant Glioma.

What interventions are being tested in trial NCT05030298?

The interventions under investigation include: Radiation Therapy (RADIATION), Temozolomide (DRUG), Radiosurgery (RADIATION), Stereotactic Biopsy (PROCEDURE), Tumor Treating Fields Therapy (PROCEDURE).

Who is sponsoring clinical trial NCT05030298?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05030298 being conducted?

This trial has 2 study locations across Arizona, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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