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NCT02500849 · ClinicalTrials.gov registry record · Phase 1

Safety Study of Zinc Finger Nuclease CCR5-modified Hematopoietic Stem/Progenitor Cells in HIV-1 Infected Patients

A Phase 1 study of HIV, sponsored by City of Hope Medical Center.

Active
Registry status
Phase 1
Development phase
12
Enrollment target
5
Study locations

NCT02500849 is a Phase 1 study of HIV that is active but no longer recruiting, run by City of Hope Medical Center. The registered enrollment target is 12 participants, below the 440-participant average among 303 other HIV trials with a reported enrollment target (97% lower). The trial reports 5 study locations across 2 states.

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The verdict

NCT02500849, a Phase 1 study of HIV, is active but no longer recruiting, sponsored by City of Hope Medical Center.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
12 participants
Enrollment target
5
Study locations

Study Summary

The purpose of the study is to evaluate the safety and feasibility of administering SB-728mR-HSPC after conditioning with busulfan.

Conditions Studied

Interventions

  • GENETIC SB-728mR-HSPC Infusion 3 days following busulfan conditioning

Study Locations (5)

California

  • City of Hope Medical Center - Duarte
  • UCLA CARE Center - Los Angeles
  • Mills Clinical Research - Los Angeles
  • Quest Clinical Research - San Francisco

Connecticut

  • Circle CARE Center, LLC - Norwalk

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2016-03-10
Est. Completion 2026-08-24
Phase Phase 1

Sponsor

City of Hope Medical Center

582 total trials

What the Registry Record Tells You About NCT02500849

The ClinicalTrials.gov registry entry for NCT02500849 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 440-participant average among 303 other HIV trials with a reported enrollment target (97% lower). The listed sponsor is City of Hope Medical Center, which has 582 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with HIV appearing as the primary indexed condition, and to 1 intervention - of which SB-728mR-HSPC Infusion 3 days following busulfan conditioning is the first listed.

NCT02500849 reports 5 study locations spanning 2 distinct geographic areas - top geographies include California, Connecticut.

Frequently Asked Questions

What is clinical trial NCT02500849 about?

NCT02500849 is a clinical study titled "Safety Study of Zinc Finger Nuclease CCR5-modified Hematopoietic Stem/Progenitor Cells in HIV-1 Infected Patients". The purpose of the study is to evaluate the safety and feasibility of administering SB-728mR-HSPC after conditioning with busulfan.

What is the current status of trial NCT02500849?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2016-03-10. Estimated completion is 2026-08-24.

What conditions does trial NCT02500849 study?

This clinical trial studies the following conditions: HIV.

What interventions are being tested in trial NCT02500849?

The interventions under investigation include: SB-728mR-HSPC Infusion 3 days following busulfan conditioning (GENETIC).

Who is sponsoring clinical trial NCT02500849?

This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02500849 being conducted?

This trial has 5 study locations across California, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.