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NCT04977336 · ClinicalTrials.gov registry record · Phase 2

A Study Evaluating Efficacy and Safety of VX-548 for Acute Pain After a Bunionectomy

A Phase 2 study of Acute Pain, sponsored by Vertex Pharmaceuticals Incorporated.

Completed
Registry status
Phase 2
Development phase
274
Enrollment target
12
Study locations

NCT04977336 is a Phase 2 study of Acute Pain that has completed, run by Vertex Pharmaceuticals Incorporated. The registered enrollment target is 274 participants, roughly in line with the 263-participant average among 50 other Acute Pain trials with a reported enrollment target. The trial reports 12 study locations across 8 states.

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The verdict

NCT04977336, a Phase 2 study of Acute Pain, has completed, sponsored by Vertex Pharmaceuticals Incorporated.

COMPLETED
Registry status
Phase 2
Development phase
274 participants
Enrollment target
12
Study locations

Study Summary

The purpose of this study is to evaluate the efficacy and safety of VX-548 doses in treating acute pain after a bunionectomy.

Conditions Studied

Acute Pain

Interventions

  • DRUG VX-548
  • DRUG HB/APAP
  • DRUG Placebo (matched to VX-548)
  • DRUG Placebo (matched to HB/APAP)

Study Locations (12)

California

  • Anaheim Clinical Trials - Anaheim
  • Lotus Clinical Research - Pasadena
  • New Hope Research Development - Tarzana

Texas

  • First Surgical Hospital - Bellaire
  • Legent Orthopedic Hospital - Carrollton
  • Endeavor Clinical Trials - San Antonio

Alabama

  • Shoals Medical Trials Inc. - Sheffield

Arizona

  • Arizona Research Center - Phoenix

Georgia

  • Atlanta Center for Medical Research - Atlanta

Maryland

  • Chesapeake Research Group - Pasadena

Ohio

  • Midwest Clinical Research Center - Dayton

Utah

  • JBR Clinical Research - Salt Lake City

Trial Details

FieldValue
Enrollment Target 274 participants
Start Date 2021-07-19
Est. Completion 2022-03-04
Phase Phase 2

Sponsor

Vertex Pharmaceuticals Incorporated

191 total trials

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What the Registry Record Tells You About NCT04977336

The ClinicalTrials.gov registry entry for NCT04977336 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 274 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 263-participant average among 50 other Acute Pain trials with a reported enrollment target. The listed sponsor is Vertex Pharmaceuticals Incorporated, which has 191 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Acute Pain appearing as the primary indexed condition, and to 4 interventions - of which VX-548 is the first listed.

NCT04977336 reports 12 study locations spanning 8 distinct geographic areas - top geographies include California, Texas, Alabama.

Frequently Asked Questions

What is clinical trial NCT04977336 about?

NCT04977336 is a clinical study titled "A Study Evaluating Efficacy and Safety of VX-548 for Acute Pain After a Bunionectomy". The purpose of this study is to evaluate the efficacy and safety of VX-548 doses in treating acute pain after a bunionectomy.

What is the current status of trial NCT04977336?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 274 participants. The study started on 2021-07-19. Estimated completion is 2022-03-04.

What conditions does trial NCT04977336 study?

This clinical trial studies the following conditions: Acute Pain.

What interventions are being tested in trial NCT04977336?

The interventions under investigation include: VX-548 (DRUG), HB/APAP (DRUG), Placebo (matched to VX-548) (DRUG), Placebo (matched to HB/APAP) (DRUG).

Who is sponsoring clinical trial NCT04977336?

This trial is sponsored by Vertex Pharmaceuticals Incorporated, which has 191 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04977336 being conducted?

This trial has 12 study locations across Alabama, Arizona, California, Georgia, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.