Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05335070 · ClinicalTrials.gov registry record · Phase 2
Reducing Pain From Wisdom Molar Extractions
A Phase 2 study of Acute Pain, sponsored by Rutgers, The State University of New Jersey.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT05335070: Recruiting Phase 2 study of Acute Pain, sponsored by Rutgers, The State University of New Jersey.
NCT05335070 is a Phase 2 study of Acute Pain that is actively recruiting participants, run by Rutgers, The State University of New Jersey. The registered enrollment target is 20 participants, below the 268-participant average among 50 other Acute Pain trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05335070, a Phase 2 study of Acute Pain, is actively recruiting participants, sponsored by Rutgers, The State University of New Jersey.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a pilot study evaluating the ability of the Temporo-masseteric Nerve Block local anesthetic injection (this was called the Twin Block earlier) to reduce pain experienced by individuals undergoing removal of lower third molar(s) under intravenous sedation. Study participants will be queried for pain experience and pain medications taken during the first post-operative week and will present for a follow-up visit on Day 8.
Primary Outcome
Every 30 minutes, the patient's pain score (Numerical Pain Rating Scale with scores from 0-10, (the NRS scale), with 0= no pain, 1-3= mild pain, 4-6= moderate pain, 7-10= severe pain) will be recorded to document peak pain score by hour 4. If the patient were to report a score from 7-10 at any time, no additional delay/pain score enquiry will take place and the patient will be directed to take the first dose of post-operative pain medication as described elsewhere.
Conditions Studied
Interventions
- DRUG Temporo-masseteric Nerve Block
Study Locations (1)
New Jersey
- The University Hospital- Dental Clinic - Newark
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2022-09-13 |
| Est. Completion | 2026-12 |
| Phase | Phase 2 |
What NCT05335070 shows while recruiting
NCT05335070 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 268-participant average among 50 other Acute Pain trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Acute Pain appearing as the primary indexed condition, and to 1 intervention - of which Temporo-masseteric Nerve Block is the first listed.
NCT05335070 reports a single indexed study location in New Jersey.
Frequently Asked Questions
What is clinical trial NCT05335070 about?
NCT05335070 is a clinical study titled "Reducing Pain From Wisdom Molar Extractions". This is a pilot study evaluating the ability of the Temporo-masseteric Nerve Block local anesthetic injection (this was called the Twin Block earlier) to reduce pain experienced by individuals undergoing removal of lower third molar(s) under intravenous sedation. Study participants will be queried f...
What is the current status of trial NCT05335070?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2022-09-13. Estimated completion is 2026-12.
What conditions does trial NCT05335070 study?
This clinical trial studies the following conditions: Acute Pain.
What interventions are being tested in trial NCT05335070?
The interventions under investigation include: Temporo-masseteric Nerve Block (DRUG).
Who is sponsoring clinical trial NCT05335070?
This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05335070 being conducted?
This trial has 1 study location across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Acute Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05335070's enrollment target sits among peer trials
20 48th of 50 higher than 1 of 50 other Acute Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Twin Block, Pain Medications and Third Molar Extractions
RECRUITING · Phase 2
-
Study of Wafermine™ for Post-bunionectomy or Abdominoplasty Pain
COMPLETED · Phase 2
-
Liposome Bupivacaine Interscalene Total Shoulder
COMPLETED · Phase 2
-
Acetaminophen Versus IV Hydromorphone for Pain in the Elderly in the ED
COMPLETED · Phase 2
-
Assessment of PF614 Effects on Experimental Pain in the Cold Pressure Test (PF614-201)
COMPLETED · Phase 2
-
A Phase 2 Study to Evaluate Analgesic Effect of IV CR845 For Pain Following Bunionectomy Surgery
COMPLETED · Phase 2
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00573339 · 20 participants
Cardiac Magnetic Resonance Imaging (MRI) Normal Reference Control Group Testing
- NCT00692939 · 20 participants · Phase 1
Autologous Stem Cell Transplantation for Crohn's Disease
- NCT00967785 · 20 participants · Phase 1
A Phase I Study of Mozobil in the Treatment of Patients With WHIMS
- NCT01406691 · 20 participants · Phase 4
Light Flashes to Treat Delayed Sleep Phase Disorder (DSPD)
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI