Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04953962 · ClinicalTrials.gov registry record · Phase 2
Study of CBP501/Cisplatin/Nivolumab Combinations in Advanced Pancreatic Cancer
A Phase 2 study, sponsored by CanBas Co..
- Completed
- Registry status
- Phase 2
- Development phase
- 36
- Enrollment target
NCT04953962: Completed Phase 2 study, sponsored by CanBas Co..
NCT04953962 is a Phase 2 study that has completed, run by CanBas Co.. The registered enrollment target is 36 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04953962, a Phase 2 study, has completed, sponsored by CanBas Co..
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 36 participants
- Enrollment target
Study Summary
Multicenter, randomized, open-label, parallel group phase 2 study to assess the efficacy and tolerance of four combinations of CBP501, cisplatin, and nivolumab administered once every 21 days to patients with stage IV exocrine pancreatic cancer and WBC \< 10,000/mm3 at screening.
Primary Outcome
Tumor assessment by RECIST v.1.1 criteria will be performed at screening, every 8 weeks starting after Cycle 1 Day 1, at the End-of-Treatment visit, and every 3 months after the End-of-Treatment visit until disease progression is observed.
Interventions
- DRUG Cisplatin
- DRUG Nivolumab
- DRUG CBP501 (16)
- DRUG CBP501 (25)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2021-12-18 |
| Est. Completion | 2023-04-14 |
| Phase | Phase 2 |
What the finished NCT04953962 record still lists
NCT04953962 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (73% lower).
The record links to 0 conditions, and to 4 interventions - of which Cisplatin is the first listed.
NCT04953962 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04953962 about?
NCT04953962 is a clinical study titled "Study of CBP501/Cisplatin/Nivolumab Combinations in Advanced Pancreatic Cancer". Multicenter, randomized, open-label, parallel group phase 2 study to assess the efficacy and tolerance of four combinations of CBP501, cisplatin, and nivolumab administered once every 21 days to patients with stage IV exocrine pancreatic cancer and WBC \< 10,000/mm3 at screening.
What is the current status of trial NCT04953962?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 36 participants. The study started on 2021-12-18. Estimated completion is 2023-04-14.
What interventions are being tested in trial NCT04953962?
The interventions under investigation include: Cisplatin (DRUG), Nivolumab (DRUG), CBP501 (16) (DRUG), CBP501 (25) (DRUG).
Who is sponsoring clinical trial NCT04953962?
This trial is sponsored by CanBas Co., which has 5 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04953962's enrollment target sits among peer trials
36 1496th of 2000 higher than 477 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00929006 · 36 participants · Early Phase 1
Acute Progesterone Suppression of Wake vs. Sleep Luteinizing Hormone Pulse Frequency in Pubertal Girls With and Without Hyperandrogenism
- NCT01891318 · 36 participants · Phase 1
Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study
- NCT02291848 · 36 participants · Phase 1
Tumor-Associated Antigen-Specific Cytotoxic T-Lymphocytes for Multiple Myeloma
- NCT02366819 · 36 participants · Phase 4
Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI