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ClinicalTrials.gov 10 recruiting now early-phase tilt

Pulmonary Fibrosis: early-phase trial registry

10 of 23 indexed Pulmonary Fibrosis trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #724 of 28,707 conditions by registered trial count.

23 US clinical trials · 10 currently recruiting · #724 of 28,707 conditions by registered trial count

Pulmonary Fibrosis: 23 US clinical trials tracked, 10 recruiting.

Pulmonary Fibrosis is the subject of 23 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is National Heart, Lung, and Blood Institute (NHLBI), running 3 of these trials.

Enrollment posture brief

Registry condition pulmonary-fibrosis

OPEN 10 | RECR 43% | LATE 1 | EARLY 6 | RANK #724 | SPON 3

Nearest open-share peer: Cigarette Smoking (43% recruiting · 46 trials)

Breast Cancer Stage II47.8%Pulmonary Fibrosis (this)43%Advanced Non-Small-Cell Lung39.1%Anxiety Disorder30.4%Barrett's Esophagus26.1%
Open-enrollment share among volume-matched conditions near Pulmonary Fibrosis

Pulmonary Fibrosis lists 10 open slots (43% of 23 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Pulmonary Fibrosis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Pulmonary Fibrosis is recruiting above its size-band peers.

    10 of 23 indexed trials (43.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Pulmonary Fibrosis trials is spread across many organizations.

    National Heart, Lung, and Blood Institute (NHLBI) accounts for 3 of 23 trials (13%). 18 distinct sponsors appear on at least one study for this condition label.

  3. Typical Pulmonary Fibrosis enrolment sits around 100 participants.

    Median target enrolment is 100 among the 23 trials that report a genuine target (sentinel values excluded). 11 of those (47.8%) plan for fewer than 100 participants.

  4. Pulmonary Fibrosis splits between interventional and observational designs.

    11 interventional and 12 observational studies make up this index (47.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 22Phase 41

Open and recent trials

23 total, page 1 of 1

RECRUITING 10,000 participants

Pulmonary Fibrosis Foundation Community Registry

Pulmonary Fibrosis Foundation

NCT05382572

RECRUITING 3,500 participants

Role of Genetic Factors in the Development of Lung Disease

National Heart, Lung, and Blood Institute (NHLBI)

NCT00001532

RECRUITING 2,000 participants

Genetic Polymorphisms in Idiopathic Pulmonary Fibrosis (IPF)

University of Pittsburgh

NCT00258570

RECRUITING 1,000 participants

Interstitial Lung Disease Research Unit Biobank

University of Kansas Medical Center

NCT05392881

RECRUITING 200 participants

Single Time Point Prediction as Earlier Diagnosis of Progressive Pulmonary Fibrosis

University of California, Los Angeles

NCT06162884

RECRUITING Phase 1 100 participants

Preliminary Evaluation of [68Ga]CBP8 in Healthy Individuals, Lung Cancer, and Idiopathic Pulmonary Fibrosis Patients

Massachusetts General Hospital

NCT03535545

RECRUITING 90 participants

Explanted Lung Tissues With Pulmonary Fibrosis

University of Chicago

NCT00515567

RECRUITING Phase 2 60 participants

Advanced Imaging for Pulmonary Fibrosis

Peter Caravan

NCT06532071

RECRUITING Early Phase 1 30 participants

FAPI PET for Lung Fibrosis

University of California, Los Angeles

NCT05365802

RECRUITING NA 30 participants

Telehealth and Onsite Maintenance Exercise in Chronic Lung Disease

MGH Institute of Health Professions

NCT06304207

ACTIVE NOT RECRUITING 800 participants

Advancing Prevention of Pulmonary Fibrosis

University of Colorado, Denver

NCT04564183

ACTIVE NOT RECRUITING 500 participants

Post Acute Sequelae of COVID-19

Vanderbilt University Medical Center

NCT04964115

ACTIVE NOT RECRUITING 315 participants

Analysis of Specimens From Individuals With Pulmonary Fibrosis

National Human Genome Research Institute (NHGRI)

NCT00084305

ACTIVE NOT RECRUITING 80 participants

Microarray Analysis of Gene Expression in Idiopathic Pulmonary Fibrosis (IPF)

University of Pittsburgh

NCT00258544

ACTIVE NOT RECRUITING Phase 2 60 participants

Assessing the Efficacy of Sirolimus in Patients With COVID-19 Pneumonia for Prevention of Post-COVID Fibrosis

University of Chicago

NCT04948203

COMPLETED 400 participants

Identification of Genes Associated With Lung Disease in Patients With Rheumatoid Arthritis

National Heart, Lung, and Blood Institute (NHLBI)

NCT00001885

COMPLETED 153 participants

Segmental Bronchoalveolar Lavage

National Heart, Lung, and Blood Institute (NHLBI)

NCT00001618

COMPLETED Phase 4 121 participants

The Study of the Use of Nintedanib in Slowing Lung Disease in Patients With Fibrotic or Non-Fibrotic Interstitial Lung Disease Related to COVID-19

Icahn School of Medicine at Mount Sinai

NCT04619680

COMPLETED NA 53 participants

A Study in People With Pulmonary Fibrosis to Monitor Cough With a Wearable Device

Boehringer Ingelheim

NCT05670587

COMPLETED NA 24 participants

Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability

University of North Carolina, Chapel Hill

NCT01615484

COMPLETED Phase 1 16 participants

Imaging of Pathologic Fibrosis Using 68Ga-FAP-2286

Thomas Hope

NCT05180162

COMPLETED Phase 1 12 participants

A Pilot Study of Aerosol Interferon-gamma for Treatment of Idiopathic Pulmonary Fibrosis

NYU Langone Health

NCT00563212

COMPLETED NA 11 participants

Oxygen Savings With Administered Oxygen and High Flow Ambient Air At Rest

Johns Hopkins University

NCT04170062

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 2
Phase 4 1

Named interventions

Most-linked intervention names on Pulmonary Fibrosis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

[68Ga]CBP8 Drug
2 trials
aerosol interferon-gamma Drug
1 trials
A wearable cough monitoring device, the Strados Labs RESPᵀᴹ sensor, with an accompanying mobile application (App) for data collection Device
1 trials
Nasal Delivery of Oxygen Therapy Device
1 trials
Nasal Delivery of High-Flow Air and Oxygen Therapy Device
1 trials
STEEN Solution™ Device
1 trials
Transplantation of lungs obtained from Non-Heart-Beating Donors (NHBDs) after ex-vivo perfusion w/ STEEN Solution™ Procedure
1 trials
High resolution CT scan of the chest Radiation
1 trials

US sites by state

Facility locations filed on Pulmonary Fibrosis trials. A trial with sites in several states counts in each.

Maryland 6 trials
Massachusetts 3 trials
Illinois 3 trials
California 3 trials
Pennsylvania 2 trials
New York 2 trials
North Carolina 2 trials
Colorado 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Pulmonary Fibrosis page

23 registered trials, 10 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Pulmonary Fibrosis condition card totals 23 registered trials; most-linked intervention [68Ga]CBP8; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.